| Outcome | Relevance (1–9) | Critical |
|---|---|---|
| Hypoglycemia | 9 | Yes |
| All-cause mortality | 8 | Yes |
| Medium-/long-term HbA1c | 8 | Yes |
| Quality of life | 8 | Yes |
| Major cardiovascular events | 7 | Yes |
| Body mass index | 7 | Yes |
| Renal function | 6 | No |
| Albuminuria | 6 | No |
| Hospitalization for heart failure | 4 | No |
| Short-term HbA1c | 3 | No |
| Genito-urinary infection | 3 | No |
| Ketosis | 2 | No |
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