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. 2023 Jun 23;13:10214. doi: 10.1038/s41598-023-37207-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of aerobic training and resistance training on expression of dermal extracellular matrix-related genes in cultured skin fibroblasts. (a) Venn diagram of dermal extracellular matrix genes with increased expression after aerobic training (AT) and resistance training (RT). Expression levels of genes in the blue and red elliptical areas were higher in plasma after the AT and RT intervention, respectively. Expression levels of genes in the overlapping area were higher in plasma after both AT and RT. (b) Differential effect of AT and RT on BGN expression. Columns and bars indicate mean and standard error (SE). Statistical analyses of intragroup differences were performed with two-sided paired t tests. **, p < 0.01; N.S. not significant, AT aerobic training, BGN biglycan, CHPF chondroitin polymerizing factor, CHSY1 chondroitin sulfate synthase 1, COL1A2 collagen type I α 2 chain, COL3A1, collagen type III α 1 chain, COL5A1 collagen type V α 1 chain, COL6A1 collagen type VI α 1 chain, COL12A1 collagen type XII α 1 chain, COL14A1 collagen type XIV α 1 chain, DCN decorin, HAS2 hyaluronan synthase 2, RT resistance training, VCAN versican.