Skip to main content
. 2023 Jun 23;13:10220. doi: 10.1038/s41598-023-36325-8

Table 1.

Characteristics of study participants aged ≥ 20 years from 1999 to 2004 National Health and Nutrition Examination Survey.

Characteristics Overall Caffeine intake (mg/day) P value
Group 1 Group 2 Group 3 Group 4
(≥ 0 to < 40 mg/day) (≥ 40 to < 200 mg/day) (≥ 200 to < 400 mg/day) (≥ 400 mg/day)
Sample size, n (%) 8993 (100) 3038 (33.78) 3446 (38.32) 1644 (18.28) 865 (9.62)
Age, y, mean (SD) 49.4 (18.8) 47.9 (20.0) 50.0 (19.4) 50.5 (17.00) 50.1 (14.8)  < 0.001
Sex, n (%)  < 0.001
 Male 4234 1232 (40.55) 1586 (46.02) 876 (53.28) 540 (62.43)
 Female 4759 1806 (59.45) 1860 (53.98) 768 (46.72) 325 (37.57)
Educational level, n (%)  < 0.001
 < High school 3062 (34.12) 1191 (39.32) 1218 (35.42) 451 (27.45) 202 (23.41)
 Completed high school 2071 (23.08) 632 (20.86) 785 (22.83) 416 (25.32) 238 (27.58)
 > High school 3841 (42.80) 1206 (39.82) 1436 (41.76) 776 (47.23) 423 (49.02)
Race/ethnicity, n (%)  < 0.001
 Non-Hispanic White 4390 (48.82) 1085 (35.71) 1611 (46.75) 1030 (62.65) 664 (76.76)
 Non-Hispanic Black 1686 (18.75) 830 (27.32) 632 (18.34) 168 (10.22) 56 (6.47)
 Other 2917 (32.44) 1123 (36.97) 1203 (34.91) 446 (27.13) 145 (16.67)
Marital status, n (%)  < 0.001
 Married/living with partner 5351 (62.76) 1666 (57.41) 2054 (62.97) 1047 (67.42) 584 (72.19)
 Widowed/divorced/separated/never married 3175 (37.24) 1236 (42.59) 1208 (37.03) 506 (32.58) 225 (27.81)
PIR, n (%)  < 0.001
 < 1.00 1502 (18.59) 655 (24.34) 572 (18.49) 188 (12.47) 87 (11.04)
 1.00 to < 2.00 2098 (25.97) 731 (27.16) 867 (28.03) 336 (22.28) 164 (20.81)
 ≥ 2.00 4480 (5545) 1305 (48.49) 1654 (53.48) 984 (65.25) 537 (68.15)
BMI category, n (%) 0.024
 < 25.0 kg/m2 2782 (31.97) 975 (33.31) 1018 (30.62) 521 (32.56) 268 (31.53)
 25.0 to < 30.0 kg/m2 3169 (36.42) 1071 (36.62) 1213 (36.48) 575 (35.94) 309 (36.35)
 ≥ 30.0 kg/m2 2751 (31.61) 880 (30.06) 1094 (32.90) 504 (31.50) 273 (32.12)
Smoking status, n (%)  < 0.001
 Never smoking 4688 (52.20) 1913 (63.11) 1833 (53.27) 703 (42.79) 239 (27.63)
 Former smoker 2383 (26.54) 656 (21.64) 931 (27.06) 515 (31.35) 281 (32.49)
 Current smoker 1909 (21.26) 462 (15.24) 677 (19.67) 425 (25.87) 345 (39.88)
Alcohol status, n (%) 5730 (66.95) 1659 (58.03) 2184 (66.81) 1203 (75.76) 684 (81.24)  < 0.001
Cancer, n (%) 756 (8.41) 218 (7.19) 321 (9.32) 149 (9.07) 68 (7.87) 0.013
Hypertension, n (%) 3961 (44.05) 1318 (43.38) 1586 (46.02) 711 (43.25) 346 (40.00) 0.007
TG, mmol/L, mean (SD) 5.20 (1.05) 5.15 (1.05) 5.21 (1.08) 5.25 (1.01) 5.23 (1.01) 0.011
Energy intake, kcal/day, mean (SD) 2084.33 (1014.68) 1941.82 (971.38) 2036.96 (982.85) 2242.28 (988.06) 2473.39 (1187.85)  < 0.001
Protein intake, g/day, mean (SD) 78.69 (42.92) 75.63 (43.52) 76.67 (41.54) 82.68 (41.83) 89.93 (45.84)  < 0.001
Calcium intake,mg/day, mean (SD) 803.14 (580.56) 788.32 (612.26) 785.70 (562.78) 826.30 (543.01) 880.64 (598.01)  < 0.001
Magnesium intake, mg/day, mean (SD) 274.17 (148.27) 265.21 (157.07) 260.07 (137.19) 287.91 (137.32) 335.68 (161.12)  < 0.001
Iron intake, mg/day, mean (SD) 15.03 (9.43) 14.75 (9.71) 14.60 (9.10) 15.52 (9.05) 16.79 (10.16)  < 0.001
Sodium intake, mg/day, mean (SD) 3231.35 (1815.33) 3013.37 (1759.74) 3125.67 (1707.05) 3510.66 (1861.69) 3887.05 (2100.39)  < 0.001

SD standard deviation, PIR poverty-income ratio (ratio of family income to poverty threshold), BMI body mass index (calculated as weight in kilograms divided by the square of height in meters), TG triglycerides.