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. 2023 Jun 23;13:10220. doi: 10.1038/s41598-023-36325-8

Table 2.

Effects of factors on severe headache or migraine in adults.

Variables Males (n = 4234) Females (n = 4759)
Statistics OR (95% Cl) P- value Statistics OR (95% Cl) P value
Age 50.50 ± 18.49 0.98(0.98,0.99)  < 0.001 48.45 ± 19.05 0.98(0.97,0.98)  < 0.001
Educational level
 < High school 1496 Reference 1566 Reference
 Completed high school 957 0.81(0.64,1.01) 0.064 1114 0.79(0.66,0.94) 0.007
 > High school 1772 0.62(0.51,0.76)  < 0.001 2069 0.75(0.65,0.87)  < 0.001
Race/ethnicity
 Non-Hispanic White 2108 Reference 2282 Reference
 Non-Hispanic Black 793 1.15(0.91,1.46) 0.231 893 1.46(1.22,1.74)  < 0.001
 Other 1333 1.15(0.94,1.40) 0.168 1584 1.60(1.39,1.85)  < 0.001
Marital status
 Widowed/divorced/separated/never married 1254 Reference 1921 Reference
 Married/living with partner 2776 0.82(0.68,0.98) 0.032 2575 1.09(0.95,1.25) 0.209
PIR
 < 1.00 638 Reference 864 Reference
 1.00 to < 2.00 988 0.65(0.50,0.84)  < 0.001 1110 0.80(0.66,0.97) 0.021
 ≥ 2.00 2210 0.45(0.36,0.57)  < 0.001 2270 0.59(0.50,0.70)  < 0.001
BMI category
 < 25.0 kg/m2 1276 Reference 1506 Reference
 25.0 to < 30.0 kg/m2 1726 0.96(0.78,1.19) 0.723 1443 1.03(0.87,1.22) 0.709
 ≥ 30.0 kg/m2 1092 1.23(0.98,1.55) 0.071 1659 1.28(1.09,1.49) 0.002
Smoking status
 Never smoking 1730 Reference 2958 Reference
 Former smoker 1415 0.96(0.78,1.19) 0.734 968 0.84(0.71,1.00) 0.050
 Current smoker 1083 1.60(1.30,1.97)  < 0.001 826 1.49(1.27,1.76)  < 0.001
Alcohol status
 No 750 Reference 2078 Reference
 Yes 3329 0.88(0.71,1.10) 0.264 2401 0.89(0.78,1.02) 0.089
Cancer
 No 3861 Reference 4368 Reference
 Yes 370 0.58(0.40,0.84) 0.004 386 0.93(0.73,1.18) 0.555
Hypertension
 No 2338 Reference 2694 Reference
 Yes 1896 0.94(0.78,1.12) 0.458 2065 0.73(0.64,0.83)  < 0.001
TG (mmol/L) 5.12 ± 1.08 0.94(0.86,1.02) 0.162 5.27 ± 1.08 0.88(0.82,0.94)  < 0.001
Energy intake (100 kcal/day) 24.10 ± 11.31 1.01(1.00,1.02) 0.007 17.94 ± 7.94 1.01(1.00,1.02) 0.004
Protein intake (100 g/day) 0.92 ± 0.48 1.20(1.01,1.42) 0.039 0.67 ± 0.34 1.09(0.90,1.31) 0.381
Calcium intake (100 mg/day) 8.82 ± 6.40 1.01(0.99,1.02) 0.283 7.33 ± 5.12 1.00(0.99,1.01) 0.754
Magnesium intake (100 mg/day) 3.13 ± 1.66 1.01(0.95,1.06) 0.821 2.40 ± 1.21 0.95(0.89,1.00) 0.044
Iron intake (100 mg/day) 0.17 ± 0.10 1.31(0.58,2.98) 0.520 0.13 ± 0.08 0.50(0.22,1.13) 0.095
Sodium intake (100 mg/day) 37.13 ± 20.30 1.00(1.00,1.01) 0.271 28.03 ± 14.73 1.00(1.00,1.01) 0.347

SD standard deviation, PIR poverty-income ratio, BMI body mass index, TG triglyceride, CI confidence interval, OR odds ratio.