Table 3.
Relationships between telomere length or telomerase and biological mediators.
| Telomere length | Telomerase | |||||
|---|---|---|---|---|---|---|
| b (95% CI) | β | p value | b (95% CI) | β | p value | |
| AL | ||||||
| Model 1 | − 0.037 (− 0.067, − 0.007) | − 0.35 | 0.0158 | 0.013 (− 0.048, 0.073) | 0.062 | 0.678 |
| Model 2 | − 0.034 (− 0.061, − 0.006) | − 0.32 | 0.0164 | 0.018 (− 0.039, 0.075) | 0.09 | 0.523 |
| Model 3 | − 0.031(− 0.061, − 0.002) | − 0.297 | 0.037 | 0.014 (− 0.046, 0.075) | 0.071 | 0.635 |
| CRP | ||||||
| Model 1 | − 0.124 (− 0.247, − 0.002) | − 0.289 | 0.047 | 0.114 (− 0.126, 0.353) | 0.139 | 0.346 |
| Model 2 | − 0.097(− 0.214, 0.021) | − 0.224 | 0.104 | 0.173 (− 0.053, 0.399) | 0.211 | 0.131 |
| Model 3 | − 0.092 (− 0.220, 0.035) | − 0.214 | 0.15 | 0.200 (− 0.045, 0.445) | 0.245 | 0.107 |
| GP | ||||||
| Model 1 | − 0.389 (− 1.10, 0.326) | − 0.159 | 0.279 | − 1.27 (− 2.59, 0.048) | − 0.275 | 0.059 |
| Model 2 | − 0.311 (− 0.977, 0.356) | − 0.127 | 0.353 | − 1.14 (− 2.39, 0.110) | − 0.247 | 0.073 |
| Model 3 | − 0.235 (− 0.915, 0.445) | − 0.096 | 0.488 | − 1.37 (− 2.62, − 0.120) | − 0.297 | 0.033 |
Model 1. Unadjusted for age.
Model 2. Adjusted for age.
Model 3. Further adjusted for Gender, Race, and Smoking status.
AL = Allostatic Load; GP = Glutathione Peroxidase; CRP = C-reactive protein.
n = 47 for correlation between with AL due to exclusion.
*Bonferroni-corrected p value for significance was p = 0.017 (0.05/3).
Significant values are in bold.