Table 2.
Numbers of newly diagnosed diabetes cases, and incidence rate ratios (with 95% confidence intervals) for newly diagnosed diabetes six months before and after COVID-19 vaccination: Disease Analyzer database (Germany).
| Period of vaccination | Newly diagnosed cases of diabetes (stratified by the date of diagnosis relative to the date of vaccination) |
IRR (95% CI) a, b |
||
|---|---|---|---|---|
| Days −183 to −1 (Diagnosis before vaccination) |
0 (Diagnosis on the day of vaccination) |
Days 1 to 183 (Diagnosis after vaccination) |
||
| April 2021 to March 2022 | 3333 | 246 | 2619 |
0.786 (0.747–0.827) |
| April 2021c | 1316 | 101 | 978 | 0.743 (0.684–0.807) |
| May 2021 | 847 | 57 | 611 | 0.721 (0.650–0.800) |
| June 2021 | 477 | 38 | 398 | 0.834 (0.730–0.953) |
| July 2021 | 254 | 17 | 205 | 0.807 (0.671–0.970) |
| August 2021 | 112 | 9 | 92 | 0.821 (0.623–1.082) |
| September 2021 | 83 | 4 | 85 | 1.024 (0.757–1.386) |
| October 2021 | 51 | 8 | 61 | 1.196 (0.825–1.735) |
| November 2021 | 76 | 2 | 72 | 0.947 (0.686–1.308) |
| December 2021 | 66 | 3 | 73 | 1.106 (0.793–1.543) |
| January to March 2022 | 51 | 7 | 44 | 0.863 (0.576–1.291) |
IRR: incidence rate ratio; CI: confidence interval.
a
without day of vaccination.
b
reference: time period before vaccination.
c
How to read: From all patients with a first COVID-19 vaccination in April 2021 with a diagnosis of diabetes 6 months before or after the vaccination, 1316 had the diagnoses of diabetes before the vaccination, and 978 had it after the vaccination.