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. 2023 Jun 9;14:1168806. doi: 10.3389/fendo.2023.1168806

Table 2.

Levels of biochemistry measurements and sex hormones in overweight and obese PCOS patients.

Mean ± SD Median
(P25, P75)
95% CI Normality test (Shapiro-Wilk) Reference Standard Number of subjects (percentage) within normal range
TG
(mmol/L)
2.06 ± 1.34 1.72
(1.27, 2.49)
0.59—6.97 p < 0.001 ≤ 1.70 N = 42 (48.3%)
TC
(mmol/L)
5.01 ± 0.97 4.82
(4.2, 5.66)
3.48—7.14 p = 0.079 ≤ 5.18 N = 52 (59.8%)
HDL-C
(mmol/L)
1.09 ± 0.21 1.05
(0.96, 1.25)
0.72—1.64 p = 0.023 > 1.04 N = 45 (51.7%)
LDL-C
(mmol/L)
3.08 ± 0.80 3.0
(2.45, 3.68)
1.72—4.93 p = 0.20 ≤ 3.34 N = 57 (65.5%)
Glucose
(mmol/L)
5.17 ± 0.58 5.07
(4.81, 5.44)
4.25—6.7 p = 0.018 ≤ 6.10 N = 83 (92.2%)
Insulin
(pmol/L)
109.91 ± 70.83 89.59
(64.23, 149.43)
13.96—335.17 p = 0.001 21—174 N =70 (80.5%)
FSH
(IU/L)
5.98 ± 1.76 5.97
(4.91, 7.25)
2.27—9.37 p = 0.942 2.5—10.2 N = 85 (97.7%)
LH
(IU/L)
9.38 ± 6.0 7.71
(4.95, 11.99)
1.91—25.33 p < 0.001 1.9—12.5 N = 66 (75.9%)
LH/FSH ratio 1.59 ± 0.91 1.28
(0.98, 2.05)
0.40—4.30 p < 0.001 ≤ 2 N = 64 (73.5%)
Estradiol
(pg/mL)
60.43 ± 45.01 49.91
(42.81, 61.3)
18.22—209.73 p < 0.001 19.5—144.2 N = 81 (93.1%)
Progesterone
(ng/mL)
1.08 ± 3.17 0.49
(0.27, 0.75)
0.03—7.59 p < 0.001 ≤ 1.4 N = 80 (92.0%)
TT
(pg/mL)
486.26 ± 216.78 439.31
(314.4, 604.54)
208.52—1065.7 p < 0.001 90—550 N = 57 (65.5%)
FT
(pg/mL)
9.02 ± 4.87 8.98
(5.93, 12.4)
1.08—20.58 p = 0.101 0.8—7.4 N = 38 (43.7%)
SHBG
(nmol/L)
48.9 ± 58.06 26.6
(16.8, 45.7)
9.02—250.0 p < 0.001 > 34.3 N = 29 (33.3%)
Prolactin
(ng/mL)
11.42 ± 5.49 10.44
(8.13, 13.35)
4.43—31.07 p < 0.001 2.8—29.2 N = 85 (97.7%)

SD, standard deviation; CI, confidence interval; TG, triglyceride; TC, total cholesterol; HDL-C, high density lipoprotein-cholesterol; LDL-C, low density lipoprotein-cholesterol; FSH, follicle stimulating hormone; LH, luteinizing hormone; LH/FSH, luteinizing hormone/follicle stimulating hormone; TT, total testosterone; FT, free testosterone; SHBG, sex hormone-binding globulin.