Table 2.
Comparison of characteristics or computed tomography (CT) findings between patients with pancreatic ductal adenocarcinoma (PDAC) and controls
| Characteristic or CT finding | Comparison between PDAC and Controls | Multivariate analysis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| At diagnosis | Past examination | 6–36 M | 36–60 M | ||||||||
| 6–36 M | 36–60 M | ||||||||||
| PDAC, (n = 54) | Control, (n = 90) | P value | PDAC, (n = 39) | Control, (n = 82) | P value | PDAC, (n = 26) | Control, (n = 90) | P‐value | P‐value | P‐value | |
| Female, n (%) | 27 (50) | 43 (47.8) | 0.864 | 22 (56.4) | 35 (42.7) | 0.177 | 11 (42.3) | 43 (47.8) | 0.661 | 0.212 | 0.547 |
| Age, years median (range) | 76 (57–89) | 76.5 (63–90) | 0.612 | 75 (56–87) | 75.5 (62–89) | 0.902 | 72 (53–85) | 72 (56–86) | 0.713 | 0.557 | 0.329 |
| Mass, n (%) | 47 (87.0) | 0 (0) | <0.0001 | 3 (7.7) | 0 (0) | 0.032 | 0 (0) | 0 (0) | NA | 0.067 | NA |
| MPD dilatation without cutoff, n (%) | 4 (4.7) | 4 (4.4) | 0.473 | 2 (5.1) | 3 (3.7) | 0.657 | 2 (7.7) | 4 (4.4) | 0.615 | 0.496 | 0.669 |
| MPD dilatation with cutoff, n (%) | 40 (74.1) | 0 (0) | <0.0001 | 11 (28.2) | 0 (0) | <0.0001 | 1 (3.8) | 0 (0) | 0.224 | <0.0001 | 0.202 |
| Cyst, n (%) | 36 (66.7) | 26 (28.9) | <0.0001 | 17 (43.6) | 24 (29.3) | 0.151 | 7 (26.9) | 23 (25.6) | 1.000 | 0.673 | 0.756 |
| Chronic pancreatitis with calcification, n (%) | 7 (13.0) | 11 (13.9) | 1.000 | 6 (15.4) | 13 (15.9) | 1.000 | 4 (15.4) | 13 (14.4) | 1.000 | 0.241 | 0.582 |
| PPA, n (%) | 27 (50.0) | 5 (5.6) | <0.0001 | 9 (23.1) | 4 (4.9) | 0.004 | 4 (15.4) | 5 (5.6) | 0.112 | 0.023 | 0.190 |
| FPA, n (%) | 4 (7.4) | 4 (4.4) | 0.473 | 6 (15.4) | 3 (3.7) | 0.031 | 3 (11.5) | 4 (4.4) | 0.186 | ‐ | ‐ |
| UPA, n (%) | 24 (44.4) | 1 (1.1) | <0.0001 | 3 (7.7) | 1 (1.2) | 0.037 | 1 (3.8) | 1 (1.1) | 0.400 | ‐ | ‐ |
| DPA, n (%) | 0 (0) | 0 (0) | NA | 3 (7.7) | 0 (0) | 0.032 | 2 (7.7) | 0 (0) | 0.049 | 0.003 | 0.009 |
DPA, diffuse parenchymal atrophy; FPA, focal parenchymal atrophy; M, months; MPD, main pancreatic duct; NA, not available; PPA, partial parenchymal atrophy; UPA, upstream parenchymal atrophy.