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. 2023 Jun 24;23:208. doi: 10.1186/s12906-023-04047-z

Table 1.

Comparison of pain, nausea and vomiting and number and dose of painkiller administration in the intervention and control groups during the study period

Variables Times Groups Test, p-value
Intervention Mean (SD) Control Mean (SD)
Pain intensity Before the intervention 5.28 (0.94) 5.60 (1.26) F = 1.88, p = 0.17a
Entering recovery room 2.75 (2.99) 3.35 (3.17) F = 4.45, p = 0.03b
4 h after entering the ward 6.42 (1.11) 6.97 (1.19) F = 5.43, p = 0.02c
8 h after entering the ward 6.46 (0.91) 6.64 (0.98) F = 1.16, p = 0.28c
12 h after entering the ward 6.20 (0.91) 6.73 (1.13) F = 6.49, P = 0.01c
16 h after entering the ward 4.91 (0.82) 6.24 (0.88) F = 65.88, p < 0.001c
Between groups ANCOVA repeated measure F = 23.89, p < 0.001c
Number of painkiller administration 24 h before the intervention 1.82 (0.64) 1.73 (0.57) t =—0.68, p = 0.49
In the recovery room 0.46 (0.69) 0.44 (0.62) t =—0.16, p = 0.87
16 h after surgery and in the ward 2.80 (0.54) 2.60 (0.53) t =—1.74, p = 0.08
Between groups repeated measure F = 1.60, p = 0.20
Dose of pethidine administration 16 h after surgery and in the ward 27.29 (7.22) 30.15 (10.11) t =—1.36, p = 0.17
Nausea and vomiting intensity Before the intervention ––––– ––––– ––––
Entering recovery room 0 (0.0) 5.75 (0.95) F = 5.06, p = 0.02d
4 h after entering the ward 0.11 (0.55) 1.45 (2.31) F = 7.92, 0.006e
8 h after entering the ward 0 (0.0) 0.54 (1.82) F = 0.72, 0.39e
12 h after entering the ward 0 (0.0) 0.06 (0.45) F = 0.07, 0.78e
16 h after entering the ward 0 (0.0) 0.04 (0.30) F = 0.07, 0.78e
Between groups ANCOVA repeated measure F = 12.94, p = 0.001

aThe use of analgesics during last 24 h, and the site of fracture as covariates

bThe type of anesthesia, the use of analgesics in pre-intra operative, and the site of fracture as covariates

cThe type of anesthesia, the use of analgesics in pre-intra and postoperative, and the site of fracture as covariates

dThe type of anesthesia and site of fracture as covariates

eThe type of anesthesia, site of fracture, and the use or non-use of anti-emetic drugs in vomiting in recovery and in the postoperative ward as covariates