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. 2023 Jun 21;11:e15592. doi: 10.7717/peerj.15592

Table 1. Information of IMRGs.

Gene symbol Ensemble Description
NUBP1 ENSG00000103274 Nucleotide-binding protein 1
FBXL5 ENSG00000118564 F-box and leucine-rich repeat protein 5
TMEM199 ENSG00000244045 Transmembrane protein 199
HJV ENSG00000168509 Hemojuvelin BMP co-receptor
ALAS1 ENSG00000023330 5′-aminolevulinate synthase 1
ALAS2 ENSG00000158578 5′-aminolevulinate synthase 2
ISCU ENSG00000136003 Iron-sulfur cluster assembly enzyme
SLC22A17 ENSG00000092096 Solute carrier family 22 member 17
FXN ENSG00000165060 Frataxin
GLRX3 ENSG00000108010 Glutaredoxin 3
SLC40A1 ENSG00000138449 Solute carrier family 40 member 1
ABCB8 ENSG00000197150 ATP binding cassette subfamily B member 8
BDH2 ENSG00000164039 3-hydroxybutyrate dehydrogenase 2
BMP6 ENSG00000153162 Bone morphogenetic protein 6
CP ENSG00000047457 Ceruloplasmin
HEPH ENSG00000089472 Hephaestin
LTF ENSG00000012223 Lactotransferrin
NDFIP1 ENSG00000131507 Nedd4 family interacting protein 1
LCN2 ENSG00000148346 Lipocalin 2
HAVCR1 ENSG00000113249 Hepatitis A virus cellular receptor 1
SCARA5 ENSG00000168079 Scavenger receptor class A member 5
FLVCR1 ENSG00000162769 Feline leukemia virus subgroup C cellular receptor 1
ABCG2 ENSG00000118777 ATP binding cassette subfamily G member 2
CYBRD1 ENSG00000071967 Cytochrome b reductase 1
SLC48A1 ENSG00000211584 Solute carrier family 48 member 1
SLC46A1 ENSG00000076351 Solute carrier family 46 member 1
LRP1 ENSG00000123384 LDL receptor related protein 1
CD163 ENSG00000177575 CD163 molecule
FLVCR2 ENSG00000119686 Feline leukemia virus subgroup C cellular receptor family member 2
SLC39A14 ENSG00000104635 Solute carrier family 39 member 14
SLC39A8 ENSG00000138821 Solute carrier family 39 member 8
SLC11A2 ENSG00000110911 Solute carrier family 11 member 2
SLC25A37 ENSG00000147454 Solute carrier family 25 member 37
HPX ENSG00000110169 Hemopexin
ERFE ENSG00000178752 Erythroferrone
TMPRSS6 ENSG00000187045 Transmembrane serine protease 6
HAMP ENSG00000105697 Hepcidin antimicrobial peptide
SLC11A1 ENSG00000018280 Solute carrier family 11 member 1
EIF2AK1 ENSG00000086232 Eukaryotic translation initiation factor 2 alpha kinase 1
STEAP2 ENSG00000157214 STEAP2 metalloreductase
HFE ENSG00000010704 Homeostatic iron regulator
CUBN ENSG00000107611 Cubilin
TFRC ENSG00000072274 Transferrin receptor
TFR2 ENSG00000106327 Transferrin receptor 2
HMOX1 ENSG00000100292 Heme oxygenase 1
HMOX2 ENSG00000103415 Heme oxygenase 2
STEAP1 ENSG00000164647 STEAP family member 1
STEAP3 ENSG00000115107 STEAP3 metalloreductase
STEAP4 ENSG00000127954 STEAP4 metalloreductase
ABCB7 ENSG00000131269 ATP binding cassette subfamily B member 7
ABCB10 ENSG00000135776 ATP binding cassette subfamily B member 10
ABCB6 ENSG00000115657 ATP binding cassette subfamily B member 6
SFXN1 ENSG00000164466 Sideroflexin 1
SFXN2 ENSG00000156398 Sideroflexin 2
SFXN3 ENSG00000107819 Sideroflexin 3
SFXN4 ENSG00000183605 Sideroflexin 4
SFXN5 ENSG00000144040 Sideroflexin 5
ATP6AP1 ENSG00000071553 ATPase H+ transporting accessory protein 1
SLC25A28 ENSG00000155287 Solute carrier family 25 member 28
ACO1 ENSG00000122729 Aconitase 1
IREB2 ENSG00000136381 Iron-responsive element binding protein 2
FTH1 ENSG00000167996 Ferritin heavy chain 1
FTL ENSG00000087086 Ferritin light chain
NCOA4 ENSG00000266412 Nuclear receptor coactivator 4
PCBP1 ENSG00000169564 Poly(rC) binding protein 1
PCBP2 ENSG00000197111 Poly(rC) binding protein 2
FTHL17 ENSG00000132446 Ferritin heavy chain like 17
TF ENSG00000091513 Transferrin
FTMT ENSG00000181867 Ferritin mitochondrial
FECH ENSG00000066926 Ferrochelatase