Table 1. Demographic and clinical characteristics of the Han population.
Continuous variables are expressed as mean ± SD, or median (25th, 75th percentiles). Categorical variables are expressed as number and percentage. The P value of the continuous variables was calculated by the independent-sample t-test. The P value of the categorical variables was calculated by χ2 test.
| Variables | Total Cohort (n = 1,326) | T2DM (n = 331) | Control (n = 995) | P value |
|---|---|---|---|---|
| Age (years) | 60.68 ± 11.14 | 61.47 ± 10.92 | 60.42 ± 11.18 | 0.140 |
| Male, n (%) | 853 (64.3%) | 221 (66.8%) | 632 (63.5%) | 0.290 |
| Smoking, n (%) | 508 (54.8%) | 116 (47.9%) | 392 (57.2%) | 0.013 |
| Drinking, n (%) | 233 (25.4%) | 53 (22.2%) | 180 (26.5%) | 0.196 |
| Hypertension, n (%) | 339 (51.9%) | 125 (61.3%) | 214 (47.7%) | 0.001 |
| BMI (kg/m2) | 25.56 ± 3.40 | 25.90 ± 3.20 | 25.45 ± 3.45 | 0.194 |
| SBP (mmHg) | 142.99 ± 31.50 | 149.68 ± 33.16 | 140.77 ± 30.63 | <0.001 |
| DBP (mmHg) | 89.32 ± 45.89 | 90.04 ± 19.24 | 89.08 ± 51.81 | 0.791 |
| HbA1c, % | 5.58 (5.28, 6.65) | 7.84 (7.46, 8.25) | 5.44 (5.19, 5.66) | <0.001 |
| FBS (mmol/L) | 6.03 ± 2.56 | 9.12 ± 2.12 | 4.99 ± 0.80 | <0.001 |
| TG (mmol/L) | 1.88 ± 1.81 | 2.04 ± 1.35 | 1.83 ± 1.94 | 0.065 |
| TC (mmol/L) | 4.10 ± 1.08 | 4.22 ± 1.18 | 4.06 ± 1.04 | 0.025 |
| HDL-C (mmol/L) | 1.09 ± 0.43 | 1.04 ± 0.32 | 1.11 ± 0.46 | 0.005 |
| LDL-C (mmol/L) | 2.55 ± 0.87 | 2.69 ± 0.92 | 2.50 ± 0.85 | 0.001 |
| Uric acid (µmol/L) | 305.94 ± 103.71 | 281.62 ± 105.83 | 314.02 ± 101.76 | <0.001 |
| BUN (mmol/L) | 6.28 ± 7.72 | 6.20 ± 5.47 | 6.30 ± 8.33 | 0.833 |
| Cr (mmol/L) | 74.37 ± 40.34 | 74.17 ± 38.69 | 74.43 ± 40.88 | 0.920 |
| LVEF, % | 63 (60, 66) | 62 (57, 65) | 63 (60, 67) | 0.002 |
| Diabetic complications | ||||
| CAD | – | 82(24.8%) | – | |
| peripheral neuropathy | – | 61(18.4%) | – | |
| diabetic retinopathy | – | 51(15.4%) | – | |
| Diabetes Medication | ||||
| Metformin | – | 178(53.8%) | – | |
| acarbose | – | 71(21.5%) | – | |
| Glinides | – | 33(9.97%) | – | |
| insulin | – | 152(45.9%) | – |
Notes.
- BMI
- body mass index
- SBP
- systolic blood pressure
- DBP
- diastolic blood pressure
- FBS
- fasting plasma glucose
- TG
- triglyceride
- TC
- total cholesterol
- HDL-C
- high-density lipoprotein cholesterol
- LDL-C
- low-density lipoprotein cholesterol
- BUN
- blood urea nitrogen
- Cr
- creatinine
- LVEF
- left ventricular ejection fractions
- CAD
- coronary atherosclerotic heart disease
The bold styling indicates that the P value is less than 0.05, and there is a significant difference between the case group and the control group.