Table 3. Genotype and allele distribution of SNPs of the Dab2 gene in the Han population.
| SNPs | T2DM, n (%) | Control, n (%) | P value | ||
|---|---|---|---|---|---|
| rs1050903 | Genotype | GG | 192 (58.71%) | 538 (54.50%) | 0.384 |
| (G >C) | GC | 117 (35.77%) | 395 (40.02%) | ||
| CC | 18 (5.50%) | 54 (5.47%) | |||
| Dominant model | GG | 192 (58.72%) | 538 (54.51%) | 0.185 | |
| GC+CC | 135 (41.28%) | 449 (45.49%) | |||
| Recessive model | CC | 18 (5.51%) | 54 (5.47%) | 0.982 | |
| GG+GC | 309 (94.49%) | 933 (94.53%) | |||
| Overdominant model | GC | 117 (35.78%) | 395 (40.02%) | 0.173 | |
| GG+CC | 210 (64.22%) | 592 (59.98%) | |||
| Allele | G | 501 (76.6%) | 1471 (74.5%) | 0.285 | |
| C | 153 (23.4%) | 503 (25.5%) | |||
| rs2255280 | Genotype | AA | 147 (45.09%) | 427 (43.30%) | 0.754 |
| (A >C) | CA | 145 (44.47%) | 462 (46.85%) | ||
| CC | 34 (10.42%) | 97 (9.83%) | |||
| Dominant model | AA | 147 (45.09%) | 427 (43.31%) | 0.573 | |
| CA+CC | 179 (54.91%) | 559 (56.69%) | |||
| Recessive model | CC | 34 (10.43%) | 97 (9.84%) | 0.757 | |
| AA+CA | 292 (89.57%) | 889 (90.16%) | |||
| Overdominant model | CA | 145 (44.48%) | 462 (46.86%) | 0.455 | |
| AA+CC | 181 (55.52%) | 524 (53.14%) | |||
| Allele | A | 439 (67.3%) | 1316 (66.7%) | 0.779 | |
| C | 213 (32.7%) | 656 (33.3%) | |||
| rs2855512 | Genotype | AA | 148 (45.26%) | 425 (43.06%) | 0.721 |
| (A >C) | CA | 145 (44.35%) | 463 (46.91%) | ||
| CC | 34 (10.39%) | 99 (10.03%) | |||
| Dominant model | AA | 148 (45.26%) | 425 (43.06%) | 0.487 | |
| CA+CC | 179 (54.74%) | 562 (56.94%) | |||
| Recessive model | CC | 34 (10.40%) | 99 (10.03%) | 0.848 | |
| AA+CA | 293 (89.60%) | 888 (89.97%) | |||
| Overdominant model | CA | 145 (44.34%) | 463 (46.91%) | 0.420 | |
| AA+CC | 182 (55.66%) | 524 (53.09%) | |||
| Allele | A | 441 (67.48%) | 1313 (66.51%) | 0.666 | |
| C | 213 (32.62%) | 661 (33.49%) | |||
| rs11959928 | Genotype | TT | 238 (72.78%) | 737 (74.67%) | 0.473 |
| (T >A) | AT | 85 (25.99%) | 231 (23.40%) | ||
| AA | 4 (1.22%) | 19 (1.92%) | |||
| Dominant model | TT | 238 (72.78%) | 737 (74.67%) | 0.499 | |
| AT+AA | 89 (27.22%) | 250 (25.33%) | |||
| Recessive model | AA | 4 (1.22%) | 19 (1.93%) | 0.402 | |
| TT+AT | 323 (98.78%) | 968 (98.07%) | |||
| Overdominant model | AT | 85 (25.99%) | 231 (23.40%) | 0.342 | |
| AA+TT | 242 (74.01%) | 756 (76.60%) | |||
| Allele | T | 561 (85.78%) | 1705 (86.37%) | 0.703 | |
| A | 93 (14.22%) | 269 (13.63%) |