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. 2022 Nov 19;34(2):276–284. doi: 10.1007/s00335-022-09968-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Integration of human and zebrafish cardiac FB. a Single-cell integration of FB of heart datasets from human and zebrafish. b UMAP embedding of the integration of FB from human and zebrafish. c Hierarchical cluster tree analysis of the fibroblast subpopulations. The orange box encircles the populations of the human FB, while the black box encircles the key cell states involved in the regeneration of FB post-injury in zebrafish. d Dotplot representation of the expression of genes essential for regeneration of FB. The expression in zebrafish is split by control and number of days post-injury (dpi)