Table 2.
Standardized mortality ratios for each cause of death following localized melanoma diagnosis.
| Cause of death | Timing of deaths after diagnosis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| < 1 year | 1 to < 5 years | 5 to < 10 years | ≥ 10 years | Total | ||||||
| Observed | SMR (95% CI) | Observed | SMR (95% CI) | Observed | SMR (95% CI) | Observed | SMR (95% CI) | Observed | SMR (95% CI) | |
| All | 3057 | 0.74 (0.72–0.77)b | 9399 | 1.18 (1.16–1.2)b | 8172 | 1.18 (1.16–1.21)b | 21,231 | 1.01 (1–1.02) | 41,859 | 1.05 (1.04–1.06)b |
| Melanoma | 699 | 1.82 (1.69–1.96)b | 6159 | 6.43 (6.27–6.59)b | 2939 | 7.18 (6.92–7.44)b | 1020 | 7.36 (6.92–7.83)b | 10,817 | 5.72 (5.62–5.83)b |
| Non-melanoma cancers | 227 | 0.26 (0.23–0.29)b | 2037 | 0.64 (0.61–0.66)b | 2027 | 0.75 (0.72–0.79)b | 1419 | 0.77 (0.73–0.82)b | 5710 | 0.66 (0.65–0.68)b |
| Non-cancer | 2131 | 0.76 (0.72–0.79)b | 9375 | 0.88 (0.87–0.9)b | 8109 | 0.88 (0.86–0.9)b | 5717 | 0.86 (0.84–0.89)b | 25,332 | 0.87 (0.86–0.88)b |
| In situ, benign or unknown behavior neoplasm | 1 | 0.04 (0–0.23)b | 49 | 0.54 (0.4–0.71)b | 61 | 0.77 (0.59–0.98)b | 48 | 0.86 (0.63–1.14) | 159 | 0.63 (0.54–0.74)b |
| Tuberculosis | 0 | 0 (0–5.86) | 1 | 0.46 (0.01–2.55) | 2 | 1.16 (0.14–4.2) | 0 | 0 (0–3.24) | 3 | 0.53 (0.11–1.55) |
| Septicemia | 37 | 0.73 (0.51–1.01) | 128 | 0.67 (0.56–0.8)b | 125 | 0.75 (0.63–0.9)b | 73 | 0.62 (0.48–0.78)b | 363 | 0.69 (0.62–0.77)b |
| Other infectious and parasitic diseases including HIV | 24 | 0.77 (0.5–1.15) | 94 | 0.83 (0.67–1.01) | 77 | 0.81 (0.64–1.01) | 52 | 0.85 (0.63–1.11) | 247 | 0.82 (0.72–0.93)b |
| Diabetes mellitus | 90 | 0.87 (0.7–1.06) | 353 | 0.91 (0.82–1.01) | 276 | 0.85 (0.75–0.95)b | 166 | 0.72 (0.61–0.84)b | 885 | 0.84 (0.79–0.9)b |
| Alzheimer’s (ICD-9 and 10 only) | 84 | 0.65 (0.52–0.81)b | 529 | 1 (0.92–1.09) | 560 | 1.11 (1.02–1.21)b | 496 | 1.23 (1.12–1.34)b | 1669 | 1.07 (1.02–1.12)b |
| Diseases of heart | 850 | 0.86 (0.8–0.92)b | 3381 | 0.93 (0.9–0.96)b | 2832 | 0.93 (0.89–0.96)b | 1876 | 0.87 (0.83–0.91)b | 8939 | 0.91 (0.89–0.93)b |
| Hypertension without heart disease | 31 | 0.86 (0.58–1.22) | 161 | 1.12 (0.96–1.31) | 141 | 1.07 (0.9–1.26) | 89 | 0.89 (0.71–1.09) | 422 | 1.03 (0.93–1.13) |
| Cerebrovascular diseases | 175 | 0.86 (0.74–1)b | 790 | 1.06 (0.99–1.14) | 609 | 0.96 (0.89–1.04) | 454 | 0.99 (0.9–1.09) | 2028 | 0.99 (0.95–1.04) |
| Atherosclerosis | 10 | 0.75 (0.36–1.38) | 47 | 1.07 (0.79–1.42) | 36 | 1.1 (0.77–1.52) | 30 | 1.5 (1.01–2.14)b | 123 | 1.12 (0.93–1.33) |
| Aortic aneurysm and dissection | 17 | 0.88 (0.51–1.41) | 50 | 0.76 (0.56–1) | 34 | 0.67 (0.47–0.94)b | 25 | 0.78 (0.5–1.15) | 126 | 0.75 (0.63–0.89)b |
| Other diseases of arteries, arterioles, capillaries | 12 | 0.85 (0.44–1.49) | 39 | 0.75 (0.54–1.03) | 36 | 0.82 (0.57–1.14) | 23 | 0.74 (0.47–1.11) | 110 | 0.78 (0.64–0.94)b |
| Pneumonia and influenza | 74 | 0.84 (0.66–1.05) | 288 | 0.9 (0.8–1.01) | 228 | 0.85 (0.75–0.97)b | 176 | 0.95 (0.82–1.11) | 766 | 0.89 (0.83–0.95)b |
| Chronic obstructive pulmonary disease and allied conditions | 136 | 0.58 (0.49–0.68)b | 579 | 0.65 (0.6–0.71)b | 486 | 0.63 (0.57–0.69)b | 341 | 0.62 (0.56–0.69)b | 1542 | 0.63 (0.6–0.66)b |
| Stomach and duodenal ulcers | 7 | 1.41 (0.57–2.9) | 14 | 0.79 (0.43–1.33) | 5 | 0.35 (0.11–0.81)b | 14 | 1.39 (0.76–2.32) | 40 | 0.85 (0.61–1.15) |
| Chronic liver disease and cirrhosis | 20 | 0.46 (0.28–0.71)b | 91 | 0.57 (0.46–0.7)b | 75 | 0.56 (0.44–0.7)b | 61 | 0.64 (0.49–0.83)b | 247 | 0.57 (0.5–0.65)b |
| Nephritis, nephrotic syndrome and nephrosis | 46 | 0.67 (0.49–0.89)b | 231 | 0.89 (0.77–1.01) | 181 | 0.8 (0.68–0.92)b | 117 | 0.74 (0.61–0.89)b | 575 | 0.8 (0.74–0.87)b |
| Complications of pregnancy, childbirth, puerperium | 0 | 0 (0–15.88) | 6 | 7.44 (2.73–16.19)b | 3 | 4.73 (0.98–13.82) | 1 | 2.97 (0.08–16.54) | 10 | 4.97 (2.39–9.15)b |
| Congenital anomalies | 3 | 0.75 (0.15–2.18) | 15 | 1.04 (0.58–1.72) | 10 | 0.85 (0.41–1.56) | 9 | 1.1 (0.5–2.09) | 37 | 0.96 (0.68–1.33) |
| Certain conditions originating in perinatal period | 0 | 0 (0–96.23) | 1 | 11.18 (0.28–62.29) | 0 | 0 (0–66.84) | 0 | 0 (0–102.45) | 1 | 4.57 (0.12–25.44) |
| Symptoms, signs and ill-defined conditions | 33 | 0.79 (0.55–1.12) | 170 | 1.08 (0.93–1.26) | 118 | 0.84 (0.7–1.01) | 77 | 0.84 (0.66–1.05) | 398 | 0.92 (0.84–1.02) |
| Accidents and adverse effects | 84 | 0.67 (0.54–0.84)b | 342 | 0.73 (0.65–0.81)b | 334 | 0.82 (0.74–0.92)b | 222 | 0.76 (0.67–0.87)b | 982 | 0.76 (0.71–0.81)b |
| Suicide and self-inflicted injury | 36 | 0.99 (0.7–1.37) | 148 | 1.13 (0.96–1.33) | 114 | 1.07 (0.88–1.29) | 61 | 0.87 (0.67–1.12) | 359 | 1.04 (0.94–1.16) |
| Homicide and legal intervention | 2 | 0.36 (0.04–1.31) | 8 | 0.44 (0.19–0.86)b | 7 | 0.51 (0.21–1.06) | 6 | 0.73 (0.27–1.59) | 23 | 0.5 (0.32–0.75)b |
| Other cause of death | 359 | 0.65 (0.59–0.72)b | 1860 | 0.86 (0.82–0.9)b | 1759 | 0.88 (0.84–0.92)b | 1300 | 0.86 (0.82–0.91)b | 5278 | 0.85 (0.83–0.87)b |
1Number of cancer patients who died due to each cause of death.
295% Confidence interval.
bP-value < 0.05.