Table 3.
Standardized mortality ratios for each cause of death following regional melanoma diagnosis.
| Cause of death | Timing of deaths after diagnosis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| < 1 year | 1 to < 5 years | 5 to < 10 years | ≥ 10 years | Total | ||||||
| Observed | SMR (95% CI) | Observed | SMR (95% CI) | Observed | SMR (95% CI) | Observed | SMR (95% CI) | Observed | SMR (95% CI) | |
| All | 1697 | 3.34 (3.19–3.51)b | 4591 | 5.93 (5.76–6.11)b | 1977 | 3.83 (3.67–4.01)b | 2372 | 1.88 (1.8–1.96)b | 10,637 | 3.48 (3.41–3.54)b |
| Melanoma | 1227 | 6.16 (5.82–6.51)b | 5068 | 15.88 (15.45–16.33)b | 978 | 12.69 (11.91–13.51)b | 189 | 11.37 (9.81–13.12)b | 7462 | 12.19 (11.92–12.47)b |
| Non-melanoma cancers | 32 | 0.47 (0.32–0.66)b | 246 | 1.15 (1.01–1.3)b | 152 | 0.98 (0.83–1.15) | 96 | 0.98 (0.8–1.2) | 526 | 0.98 (0.9–1.07) |
| Non-cancer | 438 | 1.86 (1.69–2.04)b | 1254 | 1.69 (1.59–1.78)b | 602 | 1.11 (1.02–1.2)b | 355 | 0.98 (0.88–1.09) | 2649 | 1.41 (1.35–1.46)b |
| In situ, benign or unknown behavior neoplasm | 3 | 1.51 (0.31–4.41) | 6 | 0.96 (0.35–2.09) | 5 | 1.09 (0.35–2.55) | 2 | 0.67 (0.08–2.41) | 16 | 1.01 (0.58–1.64) |
| Tuberculosis | 0 | 0 (0–70.22) | 1 | 6.43 (0.16–35.83) | 0 | 0 (0–34.87) | 0 | 0 (0–56.77) | 1 | 2.64 (0.07–14.71) |
| Septicemia | 8 | 1.92 (0.83–3.78) | 27 | 2.05 (1.35–2.98)b | 13 | 1.35 (0.72–2.3) | 8 | 1.25 (0.54–2.47) | 56 | 1.68 (1.27–2.18)b |
| Other infectious and parasitic diseases including HIV | 3 | 1.22 (0.25–3.57) | 9 | 1.14 (0.52–2.17) | 5 | 0.88 (0.29–2.05) | 2 | 0.59 (0.07–2.12) | 19 | 0.98 (0.59–1.53) |
| Diabetes mellitus | 16 | 1.91 (1.09–3.1)b | 57 | 2.14 (1.62–2.77)b | 31 | 1.61 (1.1–2.29)b | 14 | 1.11 (0.61–1.86) | 118 | 1.77 (1.46–2.11)b |
| Alzheimer’s (ICD-9 and 10 only) | 20 | 1.72 (1.05–2.66)b | 51 | 1.32 (0.99–1.74) | 37 | 1.23 (0.87–1.7) | 21 | 0.94 (0.58–1.43) | 129 | 1.26 (1.05–1.5)b |
| Diseases of heart | 170 | 2.05 (1.75–2.38)b | 470 | 1.85 (1.69–2.03)b | 189 | 1.05 (0.91–1.21) | 116 | 0.99 (0.82–1.18) | 945 | 1.49 (1.4–1.59)b |
| Hypertension without heart disease | 5 | 1.59 (0.52–3.72) | 19 | 1.84 (1.11–2.87)b | 7 | 0.89 (0.36–1.83) | 3 | 0.54 (0.11–1.57) | 34 | 1.26 (0.87–1.76) |
| Cerebrovascular diseases | 34 | 1.96 (1.36–2.74)b | 108 | 2.04 (1.68–2.47)b | 51 | 1.36 (1.01–1.79)b | 29 | 1.15 (0.77–1.66) | 222 | 1.67 (1.46–1.91)b |
| Atherosclerosis | 3 | 2.59 (0.53–7.58) | 7 | 2.25 (0.9–4.63) | 3 | 1.55 (0.32–4.53) | 4 | 3.61 (0.98–9.23) | 17 | 2.32 (1.35–3.72)b |
| Aortic aneurysm and dissection | 3 | 1.96 (0.4–5.73) | 8 | 1.79 (0.77–3.53) | 0 | 0 (0–1.26) | 0 | 0 (0–2.11) | 11 | 1.03 (0.51–1.85) |
| Other diseases of arteries, arterioles, capillaries | 3 | 2.55 (0.53–7.47) | 4 | 1.11 (0.3–2.83) | 2 | 0.78 (0.09–2.81) | 2 | 1.18 (0.14–4.27) | 11 | 1.21 (0.61–2.17) |
| Pneumonia and influenza | 15 | 1.98 (1.11–3.26)b | 37 | 1.63 (1.15–2.25)b | 18 | 1.15 (0.68–1.82) | 13 | 1.29 (0.69–2.21) | 83 | 1.48 (1.18–1.84)b |
| Chronic obstructive pulmonary disease and allied conditions | 26 | 1.38 (0.9–2.02) | 56 | 0.93 (0.7–1.21) | 24 | 0.54 (0.35–0.81)b | 16 | 0.55 (0.31–0.89)b | 122 | 0.8 (0.67–0.96)b |
| Stomach and duodenal ulcers | 0 | 0 (0–8.98) | 2 | 1.63 (0.2–5.88) | 0 | 0 (0–4.34) | 0 | 0 (0–6.69) | 2 | 0.66 (0.08–2.38) |
| Chronic liver disease and cirrhosis | 10 | 3.05 (1.46–5.6)b | 19 | 1.73 (1.04–2.71)b | 7 | 0.86 (0.35–1.77) | 3 | 0.57 (0.12–1.66) | 39 | 1.41 (1–1.93)b |
| Nephritis, nephrotic syndrome and nephrosis | 10 | 1.73 (0.83–3.18) | 34 | 1.87 (1.29–2.61)b | 16 | 1.21 (0.69–1.97) | 14 | 1.63 (0.89–2.74) | 74 | 1.62 (1.27–2.03)b |
| Complications of pregnancy, childbirth, puerperium | 1 | 70.44 (1.78–392.46)b | 1 | 21.39 (0.54–119.18) | 1 | 29.63 (0.75–165.08) | 0 | 0 (0–193.21) | 3 | 26.36 (5.44–77.05)b |
| Congenital anomalies | 0 | 0 (0–11.86) | 1 | 1.01 (0.03–5.64) | 0 | 0 (0–5.26) | 0 | 0 (0–8.23) | 1 | 0.41 (0.01–2.28) |
| Symptoms, signs and ill-defined conditions | 1 | 0.28 (0.01–1.57) | 21 | 1.87 (1.16–2.85)b | 11 | 1.31 (0.66–2.35) | 6 | 1.18 (0.43–2.56) | 39 | 1.38 (0.98–1.89) |
| Accidents and adverse effects | 13 | 1.28 (0.68–2.18) | 50 | 1.49 (1.1–1.96)b | 23 | 0.93 (0.59–1.39) | 15 | 0.91 (0.51–1.5) | 101 | 1.19 (0.97–1.44) |
| Suicide and self-inflicted injury | 16 | 5.66 (3.24–9.2)b | 22 | 2.38 (1.49–3.6)b | 12 | 1.79 (0.93–3.13) | 7 | 1.7 (0.68–3.51) | 57 | 2.49 (1.89–3.23)b |
| Homicide and legal intervention | 1 | 2.26 (0.06–12.61) | 0 | 0 (0–2.67) | 1 | 1.07 (0.03–5.98) | 0 | 0 (0–7.04) | 2 | 0.61 (0.07–2.2) |
| Other cause of death | 77 | 1.65 (1.31–2.07)b | 244 | 1.59 (1.4–1.8)b | 146 | 1.24 (1.05–1.46)b | 80 | 0.97 (0.77–1.21) | 547 | 1.37 (1.26–1.49)b |
1Number of cancer patients who died due to each cause of death.
295% Confidence interval.
bP-value < 0.05.