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. 2023 May 26;15(5):e39516. doi: 10.7759/cureus.39516

Table 3. Baseline characteristics of the included studies.

Study Year Country Journal Study Design No. of participants in the control + intervention group Cranioplasty operations compared
Honeybul [8] 2017 Australia Journal of Neurosurgery Randomised Controlled Trial 64 Autograft, titanium
Honeybul [9] 2018 Australia Acta Neurochirurgica Randomised Controlled Trial (follow-up) 62 Autograft, titanium
Liang [10] 2015 New Zealand British Journal of Neurosurgery Single Centre Retrospective Study 88 Autograft, titanium, acrylic, polyetheretherketone (PEEK)
Broughton [11] 2014 UK British Journal of Neurosurgery Single Centre Retrospective Study 87 Autograft, titanium, acrylic
Piitulainen [12] 2015 Finland World Neurosurgery Single Centre Retrospective Study 100 Autograft, bioactive fibre-reinforced composite, hydroxyapatite, other synthetic materials