Table 3.

Results of two sample paired Wilcoxon sign-rank test for QST outcomes (N = 32)

QST		Visit 1 Mean (SD)	Visit 7 Mean (SD)	Mean difference	p-value
Mechanical detection threshold (mN)
	Control site	3.04 (0.24)	3.10 (0.35)	0.06	1.000
	Pain site	3.21 (0.52)	3.24 (0.43)	0.03	0.466
Mechanical pain threshold (mN)
	Control site	6.14 (0.48)	6.25 (0.44)	0.10	0.132
	Pain site	6.00 (0.45)	6.13 (0.43)	0.13	0.071
Mechanical pain sensitivity (pain rating 0–10)
	Control site	1.96 (1.79)	1.91 (1.67)	-0.05	0.617
	Pain site	2.66 (2.11)	2.44 (1.72)	-0.22	0.439
Dynamic mechanical allodynia (pain rating 0–10)
	Control site	0.76 (1.19)	0.76 (1.03)	0.11	0.452
	Pain site	0.84 (1.38)	0.73 (0.97)	-0.05	0.975
Windup ratio (multiple average/single average)
	Control site	2.35 (5.21)	1.57 (1.37)	-0.78	0.899
	Pain site	2.57 (3.98)	2.32 (3.96)	-0.25	0.766
Vibration detection threshold (sec)
	Control site	9.64 (3.13)	10.12 (3.08)	0.32	0.516
	Pain site	6.71 (4.66)	7.12 (3.89)	0.43	0.765
Heat Limits (°C)
	Control site	43.31 (3.67)	42.51 (3.38)	-0.80	0.651
	Pain site	41.38 (3.48)	41.30 (3.10)	-0.08	0.919
Cold detection threshold (°C)
	Control site	28.58 (2.22)	28.14 (2.55)	-0.44	0.304
	Pain site	28.60 (1.43)	28.40 (1.12)	-0.20	0.304
Warm detection threshold (°C)
	Control site	35.38 (1.37)	35.70 (1.64)	0.32	0.477
	Pain site	35.82 (1.79)	36.08 (1.35)	0.26	0.029
Cold pain threshold (°C)
	Control site	18.01 (9.90)	19.32 (8.12)	1.30	0.599
	Pain site	18.63 (10.05)	20.24 (8.08)	1.61	0.583
Heat pain threshold (°C)
	Control site	40.94 (3.83)	41.51 (3.09)	0.57	0.410
	Pain site	40.65 (3.20)	40.69 (3.21)	0.03	0.978
Pressure pain threshold (kPa)
	Control site	242.79 (120.25)	228.51 (140.43)	-14.28	0.239
	Pain site	252.6 (128.6)	277.22 (175.06)	24.62	0.360

Abbreviations: QST, quantitative sensory testing; SD, standard deviation