Table 2.
Frequencies of ALDH2 rs671, MTHFR rs1801133 genotypes and alleles in patients with arteriosclerosis in single artery and patients with arteriosclerosis in multiple arteries
| Genotype/allele | Total (n = 882) | Patients with arteriosclerosis in single artery (n = 410) | Patients with arteriosclerosis in multiple arteries (n = 472) | P values |
|---|---|---|---|---|
| ALDH2 rs671 | ||||
| G/G | 395(44.8%) | 193(47.1%) | 202(42.8%) | 0.047 |
| G/A | 385(43.7%) | 181(44.1%) | 204(43.2%) | |
| A/A | 102(11.6%) | 36(8.8%) | 66(14.0%) | |
| G | 1175(66.6%) | 567(69.1%) | 608(64.4%) | 0.038 |
| A | 589(33.4%) | 253(30.9%) | 336(35.6%) | |
| HWE (χ2, P) | χ2 = 0.308, P = 0.579 | χ2 = 0.492, P = 0.483 | χ2 = 1.551, P = 0.213 | |
| MTHFR rs1801133 | ||||
| C/C | 432(49.0%) | 217(52.9%) | 215(45.6%) | 0.039 |
| C/T | 370(42.0%) | 164(40.0%) | 206(43.6%) | |
| T/T | 80(9.1%) | 29(7.1%) | 51(10.8%) | |
| C | 1234(70.0%) | 598(72.9%) | 636(67.4%) | 0.012 |
| T | 530(30.0%) | 222(27.1%) | 308(32.6%) | |
| HWE (χ2, P) | χ2 = 0.004, P = 0.951 | χ2 = 0.069, P = 0.793 | χ2 = 0.025, P = 0.875 |
HWE, Hardy Weinberg Equilibrium