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. 2023 Jun 2;44(24):2234–2243. doi: 10.1093/eurheartj/ehad339

Table 4.

Comparisons between severe and non-severe COVID-19 VRM

Characteristics Severe VRM (n = 95) Non-severe VRM (n = 385) P value
Median age (years), median (IQR) 36 (22–51) 28 (20–43) 0.017
Age group (years), n (%) 0.006
12–17 15 (16) 63 (16)
18–29 23 (24) 138 (36)
30–39 14 (15) 72 (19)
40–49 18 (19) 45 (12)
50–59 11 (12) 44 (11)
60–69 10 (11) 13 (3)
≥ 70 4 (4) 10 (3)
Sex, n (%) 0.016
Female 46 (48) 135 (35)
Male 49 (52) 250 (65)
Presenting symptoms and signs, n (%)
Chest pain or discomfort 56 (59) 231 (60) 0.851
Dyspnea 38 (40) 90 (23) 0.001
Fever 26 (27) 51 (13) <0.001
Palpitations 5 (5) 55 (14) 0.017
Vital signs on admission, mean (SD)
Systolic BP (mmHg) 104.6 (29.2) 126.6 (21.3) <0.001
Diastolic BP (mmHg) 65.0 (19.2) 77.5 (15.2) <0.001
Heart rate (b.p.m.) 88.2 (31.2) 85.9 (18.2) 0.554
Body temperature (°C) 37.0 (1.0) 36.8 (0.7) 0.151
Comorbidity, n (%)
Diabetes mellitus 2 (2) 4 (1) 0.339
Hypertension 10 (11) 17 (4) 0.021
Dyslipidemia 4 (4) 7 (2) 0.240
Coronary artery disease 0 (0.0) 2 (1) 1.000

VRM, vaccine-related myocarditis; BP, blood pressure; IQR, interquartile range; SD, standard deviation.