Table 3.

Multivariate analysis across all subjects (N = 418): factors associated with major depressive episode and psychotic disorder

	Unadjusted prevalence Ratio	Prevalence Ratio	95% CI
Major depressive episode
Daily heroin use (in the past month)	0.68	0.52	0.34 – 0.83
Duration heroin use**	1.16	1.15	0.97 – 1.38
Current methadone treatment	0.71	0.64	0.40 – 0.98
Regular poly-substance use (ref = 0)*
One substance	0.91	1.27	0.73 – 2.30
Two substances	0.82	1.23	0.61 – 2.47
Three substances	1.81	2.72	1.09 – 6.23
Current psychotic disorder
Daily heroin use (in the past month)	0.57	0.3	0.18 – 0.52
Duration heroin use**	1.22	1.17	0.95 – 1.47
Current methadone treatment	0.74	0.68	0.39 – 1.11
Regular poly-substance use (ref = 0)*
One substance	0.94	1.82	0.92 – 3.97
Two substances	1.15	2.77	1.21 – 6.50
Three substances	3.45	9.35	3.50 – 24.94

^*Regular poly-substance use. including daily heroin injection. regular methamphetamine use (≥ 4 times in the last 30 days). and alcohol misuse

^**Levels were set as follows: less than 5 years (ref); 5–10 years; 10–15 years; 15+ years. Coefficient for each level increase