TABLE 1.
Relationship between BRCA mutations and clinical characteristics
| Characteristics | N | BRCA mutations | ||
|---|---|---|---|---|
| Wild | Mutant | p | ||
| Gender | ||||
| Male | 286 | 260 (90.9%) | 26 (9.1%) | 0.327 |
| Female | 176 | 155 (88.1%) | 21 (11.9%) | |
| Age (years) | ||||
| ≤40 | 17 | 16 (94.1%) | 1 (5.9%) | 0.087 |
| 40–49 | 66 | 54 (81.8%) | 12 (18.2%) | |
| 50–59 | 138 | 130 (94.2%) | 8 (5.8%) | |
| 60–69 | 175 | 157 (89.7%) | 18 (10.3%) | |
| ≥70 | 66 | 58 (87.9%) | 8 (12.1%) | |
| Histology | ||||
| Adenocarcinoma | 377 | 341 (90.5%) | 36 (9.5%) | 0.245 |
| Squamous cell carcinoma | 75 | 66 (88%) | 9 (12%) | |
| Large cell carcinoma | 2 | 1 (50%) | 1 (50%) | |
| Small cell lung cancer | 2 | 2 (100%) | 0 (0%) | |
| Not specified | 6 | 5 (83.3%) | 1 (16.7%) | |