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. 2023 Jun 19;5(6):1014–1028. doi: 10.1038/s42255-023-00813-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 5 — The Emont, et al. dataset³⁵ queried for: a, Canonical Wnt target genes expression. b, Dot-plot of the top 40 SWAT cell marker genes filtered by human adipose tissue depot. c, d Dot plots of top 40 ADIPOQ⁺ cell (c) and SWAT cell (d) marker genes, grouped by cell type (ASPC, Adipocyte) and body mass index (BMI). e, Bar graph of Mgp log₂ fold change values from four separate differential expression analyses of primary mouse mesenchymal progenitors isolated directly from β-Catenin^fl/fl mice from Bagchi, et al. dataset⁸. Non-adipogenic-induced progenitor (annotated as ‘Day 0’) or progenitors underwent 12-day adipogenic induction (annotated as ‘Day 12’) were harvested for RNA-seq under Wnt perturbations: Day 0 or Day 12 cells were either induced for β-catenin knockout (annotated as ‘KO’) or were treated with 20 ng/ml recombinant Wnt3a or vehicle for 4 hours before harvest (n = 4 per group). f, Dot-plot of Wnt ligand expression in all human adipose tissue cell types, from the Emont, et al. dataset³⁵.

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