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. 2023 Jun 12;13:1183318. doi: 10.3389/fonc.2023.1183318

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Copyright © 2023 Zerella, Homan, Arts, Brown, Scott and Hahn

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcription factor expression in hematopoietic cells in human hematopoiesis Vs AML. Heatmap correlating the expression levels of TFs in hematopoietic cells in human hematopoiesis with AML. The mRNA expression levels of microarray data (log2) in the ‘Normal human hematopoiesis (DMAP)’ and ‘normal hematopoiesis with AML’ datasets from BloodSpot were used, where the probe with the overall highest intensity was selected and each quadruplicate/triplicate/duplicate averaged. TFs included those selected in Table 1 (56). common myeloid progenitor, CMP; dendritic cell, DC; Erythroid, Eryth; granulocyte/monocyte progenitor, GMP;CFU; colony forming unit, granulocyte, Gran; megakaryocyte/erythroid progenitor, MEP; mature natural killer, NK; natural killer T cell, NKT; memory. mem.