Table 5.

Uni and multivariate analysis of the relationship between the time to colonoscopy and the severity of the detected CRC lesions.

Covariables	Severity risk analysis
	Univariate		Multivariate (n=1973 CRC)
	ORb[CI95 %]	P > |z|	ORa[CI95 %]	P > |z|
Time (in month) to colonoscopy (Ref. : ≤ 1Mois)
]1-3Month]	0.5 [0.4 ; 0.7]	<10-3	0.5 [0.4 ; 0.7]	<10-3
]3-7Mnth]	0.5 [0.4 ; 0.7]	<10-3	0.5 [0.4 ; 0.7]	<10-3
> 7Month	0.4 [0.3 ; 0.5]	<10-3	0.4 [0.3 ; 0.6]	<10-3
Gender (Ref. : Female)
Male	0.9 [0.8 ; 1.1]	0.24	0.9 [0.8 ; 1.1]	0.38
Age (Ref. : 50-54y)
55 – 59y	1.1 [0.8 ; 1.5]	0.43	1.1 [0.8 ; 1.5]	0.46
60 – 64y	1.1 [0.8 ; 1.4]	0.56	1.2 [0.9 ; 1.5]	0.30
65 – 69y	1.1 [0.9 ; 1.5]	0.31	1.1 [0.9 ; 1.6]	0.13
≥ 70y	1.3 [1.0 ; 1.7]	0.02	1.5 [1.0 ; 1.9]	0.007
Nb of previoous FIT (Ref. : None)
1	0.9 [0.7 ; 1.1]	0.33	0.9 [0.7 ; 1.1]	0.30
≥ 2	0.8 [0.7 ; 1.0]	0.06	0.8 [0.7 ; 1.0]	0.02
Health Insurance Schemes (Ref. General Schemes)
MGEN/MFP	1.0 [0.7 ; 1.3]	0.79	1.0 [0.7 ; 1.3]	0.88
RATP/SNCF	0.6 [0.3 ; 1.2]	0.13	0.5 [0.3 ; 1.2]	0.12
Other schemes	0.9 [0.7 ; 1.3]	0.63	1.0 [0.7 ; 1.4]	0.86
Campaign year (Ref. : 2017)
2018	1.1 [0.9 ; 1.3]	0.54	1.1 [0.9 ; 1.3]	0.58
2019	1.0 [0.8 ; 1.2]	077	1.0 [0.8 ; 1.2]	0.78
2020	0.9 [0.8 ; 1.2]	0.65	1.0 [0.8 ; 1.2]	0.71
Estimated multivariate ologit model constants
/cut 1			-1.6 [-1.9 ; 1.2]
/cut 2			-0.2 [-0.6 ; 0.1]
/cut 3			0.6 [0.2 ; 0.9]
/cut 4			2.3 [1.9 ; 2.7]

CI95 % :  95 % Confident interval ; CRC severity level (Level-0 : CCR (T0) without lymph node involvement (N0/M0) ; Level-1 : CCR (T1/T2) without lymph node involvement (N0/M0) ; Level-2 : CCR (T3/T4) without lymph node involvement (N0/M0) ; Level-3 : CRC (T1-T4) with nodal involvement ; Level-4 :  CRC with metastasis (M1)) ; OR_b : Odds-Ration brut ; OR_a : Odds-Ration ajusté ; MGEN :  Mutuelle Générale de l'Education Nationale ; MFP : Mutuelle de la Fonction Publique ; RATP : Régie Autonome des Transports Parisiens ; SNCF : Société Nationale des Chemins de Fer.