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. 2023 Jun 26;9(3):00702-2022. doi: 10.1183/23120541.00702-2022

FIGURE 3.

FIGURE 3

Patients in the lowest quartile of circulating factor B levels demonstrate increased mortality during acute respiratory distress syndrome. a) Patient survival at 90 days from intensive care unit (ICU) admission date by factor B grouped by relationship to 25th percentile (<25th percentile hazard ratio (HR) 1.70, 95% CI 1.02–2.82) in the Lisofylline and Respiratory Management of Acute Lung Injury (LARMA) cohort. b) Patient survival at 90 days from ICU admission date by factor B grouped by relationship to 25th percentile (<25th percentile HR 2.61, 95% CI 1.57–4.35) in the Statins for Acutely Injured Lungs from Sepsis (SAILS) cohort. c) Meta-analysis of factor B stratified by relationship to 25th percentile. Survival estimates in all cohorts are adjusted for age, sex and modified sequential organ failure assessment score and are presented as HR (95% CI). ALIR: University of Pittsburgh Acute Lung Injury Registry and Biospecimen Repository cohort.