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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Drug Alcohol Depend. 2023 Feb 10;245:109804. doi: 10.1016/j.drugalcdep.2023.109804

Table 5.

MOUD strategy medications by site, setting, and opioid-related deaths per 100,000

Study Sites Setting Deaths per 100 k a Total
KY MA NY OH Rural Urban <30.91 >30.91
Number of Communities 8 8 8 9 15 18 16 17 33
Strategies Selected, n 89 55 71 43 106 152 120 138 258
Medications across MOUD strategies b
Buprenorphine b 85 (95.5) 51 (92.7) 68 (95.8) 29 (67.4) 97 (91.5) 136 (89.5) 109 (90.8) 124 (89.9) 233 (90.3)
Methadone b 25 (28.1) 27 (49.1) 36 (50.7) 3 (7.0) 27 (25.5) 64 (42.1) 42 (35.0) 49 (35.5) 91 (35.3)
Naltrexone b 71 (79.8) 36 (65.5) 41 (57.7) 12 (27.9) 65 (61.3) 95 (62.5) 62 (51.7) 98 (71.0) 160 (62.0)
Expand MOUD Availability b 23 (25.8) 16 (29.1) 26 (36.6) 14 (32.6) 33 (31.1) 46 (30.3) 41 (34.2) 38 (27.5) 79 (30.6)
Buprenorphine c 22 (95.7) 15 (93.8) 26 (100.0) 12 (85.7) 32 (97.0) 43 (93.5) 41 (100.0) 34 (89.5) 75 (94.9)
Methadone c 3 (13.0) 4 (25.0) 12 (46.2) 1 (7.1) 6 (18.2) 14 (30.4) 12 (29.3) 8 (21.1) 20 (25.3)
Naltrexone c 18 (78.3) 10 (62.5) 13 (50.0) 4 (28.6) 18 (54.5) 27 (58.7) 18 (43.9) 27 (71.1) 45 (57.0)
Linkage to MOUD b 32 (36.0) 21 (38.2) 33 (46.5) 18 (41.9) 40 (37.7) 64 (42.1) 50 (41.7) 54 (39.1) 104 (40.3)
Buprenorphine d 30 (93.8) 20 (95.2) 32 (97.0) 11 (61.1) 38 (95.0) 55 (85.9) 45 (90.0) 48 (88.9) 93 (89.4)
Methadone d 12 (37.5) 9 (42.9) 17 (51.5) 1 (5.6) 13 (32.5) 26 (40.6) 17 (34.0) 22 (40.7) 39 (37.5)
Naltrexone d 28 (87.5) 12 (57.1) 21 (63.6) 4 (22.2) 24 (60.0) 41 (64.1) 26 (52.0) 39 (72.2) 65 (62.5)
MOUD Engagement and Retention b 34 (38.2) 18 (32.7) 12 (16.9) 11 (25.6) 33 (31.1) 42 (27.6) 29 (24.2) 46 (33.3) 75 (29.1)
Buprenorphine e 33 (97.1) 16 (88.9) 10 (83.3) 6 (54.5) 27 (81.8) 38 (90.5) 23 (79.3) 42 (91.3) 65 (86.7)
Methadone e 10 (29.4) 14 (77.8) 7 (58.3) 1 (9.1) 8 (24.2) 24 (57.1) 13 (44.8) 19 (41.3) 32 (42.7)
Naltrexone e 25 (73.5) 14 (77.8) 7 (58.3) 4 (36.4) 23 (69.7) 27 (64.3) 18 (62.1) 32 (69.6) 50 (66.7)

MOUD= Medication for opioid use disorder;

a

Each community’s death rate is the median of its 2018, 2019, 2020 yearly rates.

b

n (%) of all MOUD strategies;

c

n (%) of MOUD expansion strategies;

d

n (%) of MOUD linkage strategies;

e

n (%) of MOUD engagement and retention strategies;

e

Type of MOUD under bold faced header are not additive since a strategy could include multiple medications