Table 2.

Reduction in VLU area in studies included in the effect size meta-analysis.

Study Title	Participants	HBOT		Control
	(n = )	Mean Δ VLU Area	SD	Mean Δ VLU Area	SD	SMD		95%CI
Thistlethwaite 2018	29	95(%)	6.53	54	6.78	5.98		4.28	7.69
ElSharnoby 2022	25	5.46	2.03	4.42	1.92	.51		−.29	1.31
Pooled	54					3.21		2.12	8.54

Δ VLU area = change in venous leg ulcer area SD = Standard deviation 95% CI = 95% confidence interval SMD = Standardized mean difference.