Table 5.
Effect Size meta-analysis of reduction in VLU area in Randomized Controlled Trials.
| Study Title | Participants | HBOT | Control | SMD | 95%CI | |||
|---|---|---|---|---|---|---|---|---|
| (n = ) | Mean Δ VLU Area | SD | Mean Δ VLU Area | SD | ||||
| Hammarlund 1994 | 16 | 35.17(%) | 17 | 2.7 | 11 | 2.18 | .94 | 3.42 |
| Ahmad 2008 | 20 | 1.68 | .27 | .77 | .23 | 3.47 | 2.09 | 4.86 |
| Thistlethwaite 2018 | 29 | 95(%) | 6.53 | 54 | 6.78 | 5.98 | 4.28 | 7.69 |
| Longobardi 2020 (6 weeks) | 48 | 67.46 | 40.05 | 59.72 | 33.86 | .20 | −.34 | .76 |
| Longobardi 2020 (3 weeks) | 51 | 29.75(%) | 26.48 | 31.3 | 15 | −.06 | −.63 | .50 |
| Pooled | 164 | 2.2 | .55 | 3.84 | ||||
Δ VLU area = change in venous leg ulcer area SD = Standard deviation 95% CI = 95% confidence interval SMD = Standardized mean difference.