Table 4.
Association between neighborhood indices and gastroschisis among women with at least one geocoded address during the periconceptional period, National Birth Defects Prevention Study, 1997 – 2011
| Case n = 1,269 | Crude ORs (95% CIs) | Adjusted ORs (95% CIs)a | |
|---|---|---|---|
|
| |||
| NDI | |||
| T1 (Low deprivation) | 246 | Ref | Ref |
| T2 | 454 | 1.9 (1.6 – 2.2) | 1.2 (1.0 – 1.5) |
| T3 (High deprivation) | 569 | 2.3 (2.0 – 2.7) | 1.3 (1.1 – 1.6) |
|
| |||
| nSEPI | |||
| T1 (High nSEP) | 240 | Ref | Ref |
| T2 | 449 | 1.9 (1.6 – 2.2) | 1.2 (1.0 – 1.5) |
| T3 (Low nSEP) | 580 | 2.4 (2.1 – 2.8) | 1.3 (1.1 – 1.6) |
T1: Tertile 1; T2: Tertile 2; T3: Tertile 3; NDI: Neighborhood Deprivation Index; nSEPI: Neighborhood Socioeconomic Position Index
High tertile scores reflect high deprivation (NDI) or lower nSEP (nSEPI). Low tertile scores reflect low deprivation (NDI) or high nSEP (nSEPI).
Adjusted for maternal race/ethnicity (Non-Hispanic Black, Non-Hispanic White, Hispanic, Other), infant birth year (1997 – 2004, 2005 – 2009, 2010 – 2011), household income (<$10,000 $10,000 – $50,000, >$50,000), maternal education (0–11, 12 and > 12 years), and duration of residence