Table 2. Selectivity Indices Calculated for Each Tumor Cell Linea.
| compound | HeLa | MDA-MB-231 | MCF-7 | HCT-116 | A2780 | A2780cisR |
|---|---|---|---|---|---|---|
| 1 | 0.46 | 0.71 | 0.23 | 2.13 | 0.89 | 2.80 |
| 2 | 0.74 | 1.48 | 0.37 | 1.35 | 5.49 | 5.35 |
| 3 | 1.06 | 1.86 | 1.63 | 3.35 | 5.58 | 5.15 |
| 4 | 1.03 | 1.10 | 0.97 | 1.78 | 6.40 | 4.00 |
| cisplatin | 0.50 | 0.33 | 0.53 | 0.88 | 2.07 | 0.37 |
| DCF | 1.78 | 2.38 | 1.72 | 2.11 | 1.86 | 3.22 |
| enDCF | 1.93 | 1.81 | 1.57 | 2.15 | ND | ND |
SIs were calculated as IC50 (MRC-5)/IC50 (individual cancer cell line).