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. 2023 Jun 12;11:1145645. doi: 10.3389/fpubh.2023.1145645

Table 9.

Most frequent symptoms included in SAEs reports for different age and sex groups for COVID-19, Influenza and HPV vaccines.

COVID-19 vaccines Influenza vaccines HPV vaccines
Adolescents, males SAEs reports 1,257 203 201
Most frequent relevant symptoms

  • Troponin increased (34.3%)

  • Chest pain (32.6%)

  • Myocarditis (23.8%)

  • Electrocardiogram abnormal (16.8%)

  • Dyspnea (5.9%)

  • C-reactive protein increased (5.6%)

  • Pericarditis (3.8%)

  • Appendicitis (3.2%)

  • Brain natriuretic peptide increased (3.0%)

  • Dyspnea (6.9%)

  • Guillain-Barré syndrome (5.9%)

  • Immunoglobulin therapy (5.9%)

  • Convulsion (4.4%)

  • Chest pain (3.9%)

  • Gait disturbance (3.9%)

  • Platelet count decreased (4.0%)

  • Dizziness (3.5%)

  • Pain in extremity (3.5%)

  • Syncope/loss of consciousness (6.5%)

  • Immunoglobulin therapy (5.5%)

  • Convulsion (4.5%)

  • Dyspnea (4.5%)

  • Chest pain (4.0%)

  • Platelet count decreased (4.0%)

  • Seizure (4.0%)

  • Type I diabetes mellitus (4.0%)
Adolescents, females SAEs reports 638 1,308
Most frequent relevant symptoms

  • Chest pain (8.8%)

  • Dyspnea (5.9%)

  • Troponin increased (5.6%)

  • Seizure (4.7%)

  • Myocarditis (4.4%)

  • Syncope / loss of consciousness (3.6%)

  • C-reactive protein increased (3.4%)

  • Dizziness (3.4%)

  • Syncope / loss of consciousness (9.9%)

  • Dizziness (7.6%)

  • Convulsion (6.4%)

  • Dyspnea (4.3%)

  • Pain in extremity (4.0%)
Young adults, males SAEs reports 8,248 590 -
Most frequent relevant symptoms

  • Chest pain (12.9%)

  • Dyspnea (9.5%)

  • Myocarditis (7.1%)

  • Troponin increased (5.7%)

  • Thrombosis (4.8%)

  • Myocardial infarction (4.0%)

  • Pulmonary embolism (3.8%)

  • Tinnitus (3.3%)

  • Dizziness (3.1%)

  • Electrocardiogram abnormal (3.0%)

  • Paraesthesia (8.3%)

  • Guillain-Barré syndrome (7.6%)

  • Pain in extremity (7.1%)

  • Dyspnea (4.9%)

  • Dizziness (4.7%)

  • Paralysis (4.4%)

  • Chest pain (4.2%)

  • Immunoglobulin therapy (3.5%)

 -
Young adults, females SAEs reports 12,181 1,152 -
Most frequent relevant symptoms

  • Dyspnea (9.5%)

  • Chest pain (6.4%)

  • Dizziness (5.0%)

  • Thrombosis (4.5%)

  • Pain in extremity (4.2%)

  • Pulmonary embolism (4.0%)

  • Guillain-Barré syndrome (10.8%)

  • Dyspnea (10.0%)

  • Paraesthesia (7.7%)

  • Pain in extremity (5.6%)

  • Dizziness (4.3%)

  • Immunoglobulin therapy (4.0%)

 -

Percentages are referred to the total number of distinct reports in each category (each report may contain many symptoms). Symptoms with percentages less than 3% are not included.