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. 2023 Jun 12;14:1199427. doi: 10.3389/fimmu.2023.1199427

Table 11.

Studies concerning the production and application of IgY antibodies specific to Fusobacterium nucleatum.

Immunogen Activity/Properties Reference
Formaldehyde-fixed F. nucleatum (JCM 11024) In vitro and mice model; oral administration; inhibition of F. nucleatum growth and biofilm formation, decrease in alveolar bone loss Xu et al. (220)
IgY against F. nucleatum obtained by Maxam Ltd. (China) In vitro and halitosis and periodontitis rat model; reduced alveolar bone loss, decreased level of IL-6 and TNF-α Wang et al. (221)

If not specified in the Activity/Properties column, then FCA/FIA was used as an adjuvant.