Table 11.
Studies concerning the production and application of IgY antibodies specific to Fusobacterium nucleatum.
Immunogen | Activity/Properties | Reference |
---|---|---|
Formaldehyde-fixed F. nucleatum (JCM 11024) | In vitro and mice model; oral administration; inhibition of F. nucleatum growth and biofilm formation, decrease in alveolar bone loss | Xu et al. (220) |
IgY against F. nucleatum obtained by Maxam Ltd. (China) | In vitro and halitosis and periodontitis rat model; reduced alveolar bone loss, decreased level of IL-6 and TNF-α | Wang et al. (221) |
If not specified in the Activity/Properties column, then FCA/FIA was used as an adjuvant.