Table 13.

Studies concerning the production and application of IgY antibodies specific to Staphylococcus aureus.

Immunogen	Activity/Properties	Reference
Formaldehyde-fixed S. aureus (CVCC545)	In vitro; growth inhibition; S. aureus growth inhibition and increase in phagocytosis	Zhen et al. (231)
SpA protein from S. aureus	In vitro, growth inhibition; S. aureus growth inhibition	Kota et al. (232)
Formaldehyde-fixed S. aureus (ATCC 33593)	In vitro; growth inhibition; high inhibitory capacity of anti–S. aureus IgY; alhydrogel adjuvant	Guimarães et al. (233)
Formaldehyde-fixed S. aureus strains (ATCC 49521, 49525, 55804 (non-encapsulated))	Bovine mammary epithelial cell line; significant reduction of intracellular S. aureus in bovine mammary epithelial cells	Wang et al. (234)
Formaldehyde-fixed S. aureus (CVCC545)	Cows with experimental and clinical mastitis; intramammary infusion, high rate of the cure in experimental and clinical mastitis	Zhen et al. (235)

If not specified in the Activity/Properties column, then FCA/FIA was used as an adjuvant.