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. Author manuscript; available in PMC: 2023 Jun 26.
Published in final edited form as: Biol Blood Marrow Transplant. 2019 Apr 17;25(8):1603–1610. doi: 10.1016/j.bbmt.2019.04.017

FIGURE 4.

FIGURE 4.

Model-predicted dose of clofarabine in mg/kg aimed to achieve a daily AUC0–24 of 1.04mg•hr/L for (A) 0–20 years of age and (B) 0–2 years of age. The dashed line in plot (A) represents the doses at corresponding ages based on the conventional dose 40mg/m2. The dashed line in plot (B) represents the modified regimen of 1.33 kg in young children.