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. 2023 Jun 26;54:51. doi: 10.1186/s13567-023-01185-7

Table 2.

Some major physiological functions of parasites and associated differentially expressed genes found in this study

Function Gene Log2 fold change (p value < 0.001)
T. bryosalmonae (brown trout vs. rainbow trout)
Adherens junctions linking proteins Catenin beta-like −3.879
Actin polymerization ras-like GTP-binding protein Rho1 isoform X2 −3.985
ras-related GTP-binding protein A 2.796
ras-related protein Rac1 −14.379
T-cell activation Rho GTPase-activating protein −1.711
rho GTPase-activating protein 5 isoform X1 1.361
rho GTPase-activating protein 39-like 1.948
rho-associated protein kinase 1 isoform X1 1.980
Afadin isoform X5 5.159
Adhesion molecules Putative alpha P integrin isoform X1 −3.688
Neural cell adhesion molecule 2 5.028
Tight junction proteins Tetraspanin-9 1.769
Tetraspanin-4 2.245
Extracellular matrix fibronectin type-III domain-containing protein 3 A isoform X1 1.295
collagen alpha-1 (XII) chain 3.639
matrix metalloproteinase-25-like 3.271
Integrin-cytoskeleton links talin-1 isoform X1 1.55
alpha-actinin-1 isoform X3 2.113
alpha-actinin, sarcomeric-like isoform X2 −5.290
AChain A, X-ray structure of the human alpha-actinin isoform 3 −3.039
Nucleotide transporter adenosine 3’-phospho 5’-phosphosulfate transporter 1 4.3565
Amino acid transporters ATP-binding cassette sub-family G member 4-like 1.801
ATP-binding cassette sub-family A member 12 1.537
high affinity cationic amino acid transporter 1-like 3.088
cationic amino acid transporter 2-like 3.310
Ion transporters (channel/Pore type transporters) solute carrier organic anion transporter family member 4A1 isoform X2 −1.594
vesicular glutamate transporter 2-like 2.149
voltage-dependent calcium channel type A subunit alpha-1-like 4.013
voltage-dependent N-type calcium channel subunit alpha-1B-like isoform X1 5.495
Ion transporters (ATP driven Na + dependent or cotransporters Kanadaptin 1.478
putative glycerol-3-phosphate transporter 5 1.407
Cell signalling EGF-like domain-containing protein 6.451
CREB-binding protein −5.874

The table describes some of the key physiological functions of differentially expressed transcripts identified in this study. The log2 fold change of the parasite transcripts between brown trout and rainbow trout at a p value < 0.001 are presented.