Table 1.
Characterization of pApoE2 Entrapped Liposomesa
| formulation | particle size (nm) | zeta potential (mV) | PDI | entrapment efficiency (%) |
|---|---|---|---|---|
| plain liposomes | 178.6 ± 0.90 | 16.4 ± 0.5 | 0.302 ± 0.18 | 86.78 ± 1.62 |
| MAN liposomes | 160.9 ± 7.44* | 14.9 ± 5.8 | 0.238 ± 0.12 | 83.79 ± 4.44 |
| Pen liposomes | 171.5 ± 4.91# | 19.9 ± 1.3 | 0.230 ± 0.09 | 88.40 ± 6.20 |
| PenMAN liposomes | 172.0 ± 3.09#^ | 19.0 ± 0.9 | 0.191 ± 0.04 | 86.30 ± 1.55 |
| RVG liposomes | 154.6 ± 3.96*+ | 18.5 ± 0.1 | 0.249 ± 0.01 | 85.50 ± 2.25 |
| RVGMAN liposomes | 167.8 ± 2.47*^ | 19.8 ± 3.6 | 0.132 ± 0.10 | 84.50 ± 5.90 |
a
Data represent mean ± SD of four replicates.
*, #, +, and ^ indicate statistically (p < 0.05) different from plain, MAN, Pen, and RVG liposomes, respectively.