Table 4.
Correlation between clinical, operative, and both preoperative and postoperative radiographic variables with patient-reported Muscular Dystrophy Spine Questionnaire total scores: Quantitative clinical, operative and radiographic variables were assessed for correlation with Muscular Dystrophy Spine Questionnaire total scores by linear regression analysis; standardised coefficients are displayed
|
Clinical/radiological variable
|
Value/coefficient estimate (95%CI)
|
P value
|
| Clinical/Operative parameters | ||
| Postoperative follow-up (yr) | -0.766 (-1.138, -0.394) | 0.001a |
| Age (yr) | -0.651 (-1.086, -0.216) | 0.006a |
| Age at loss of independent ambulation (yr) | 0.496 (0.127, 0.865) | 0.013a |
| Age at surgery (yr) | -0.146 (-0.519, 0.227) | 0.410 |
| Preoperative gastrostomy (Y/N)1 | -0.036 (-1.072, 1.001) | 0.941 |
| Preoperative NIV use (Y/N)1 | 0.110 (-0.731, 0.951) | 0.777 |
| Duration of surgery (minutes) | -0.030 (-0.603, 0.543) | 0.911 |
| Intraoperative blood loss (%, TBV) | -0.297 (-0.841, 0.247) | 0.257 |
| Instrumented fused to pelvis (Y/N)1 | 0.542 (-0.221, 1.306) | 0.145 |
| Length of ICU stay (days) | 0.123 (-1.010, 1.255) | 0.817 |
| Length of stay in hospital (days) | -0.535 (-1.663, 0.593) | 0.322 |
| Postoperative complications (Y/N)1 | 0.010 (-0.703, 0.723) | 0.975 |
| Preoperative radiographic parameters | ||
| Scoliosis (Cobb angle) (°) | 0.268 (-5.330, 5.867) | 0.907 |
| Scoliosis on traction radiographs (Cobb angle) | -2.771 (-9.706, 4.164) | 0.351 |
| Scoliosis flexibility index (%) | -2.797 (-6.952, 1.359) | 0.144 |
| Pelvic obliquity (°) | -0.531 (-4.784, 3.723) | 0.761 |
| Pelvic obliquity on traction radiographs (°) | 1.036 (-4.511, 6.582) | 0.651 |
| Pelvic obliquity flexibility index (%) | 1.368 (-2.465, 5.200) | 0.401 |
| Lumbar lordosis (T12-S1; °) | 0.346 (-1.880, 2.571) | 0.706 |
| Thoracic kyphosis (T5-T12; °) | 0.153 (-2.283, 2.589) | 0.878 |
| Sagittal balance (C7PL, cm) | 0.533 (-1.041, 2.106) | 0.424 |
| Coronal balance (C7PL, cm) | 0.213 (-1.401, 1.828) | 0.748 |
| Postoperative radiographic parameters | ||
| Scoliosis (Cobb angle) (°) | -3.005 (-4.718, -1.292) | 0.004a |
| Correction of scoliosis (%) | 2.167 (1.053, 3.282) | 0.002a |
| Pelvic obliquity (°) | 0.367 (-0.765, 1.499) | 0.468 |
| Correction of pelvic obliquity (%) | 0.433 (-0.263, 1.129) | 0.185 |
| Lumbar lordosis (T12-S1; °) | -0.642 (-1.184, -0.100) | 0.027a |
| Thoracic kyphosis (T5-T12; °) | 0.043 (-0.345, 0.430) | 0.802 |
| Sagittal balance (C7PL, cm) | -0.190 (-0.768, 0.389) | 0.464 |
| Coronal balance (C7PL, cm) | 0.886 (-0.215, 1.987) | 0.099 |
Indicates qualitative variable.
Indicates statistically significant result (P < 0.05).
L: Luque sublaminar wires; C7PL: C7 plumb line; NIV: Non-invasive ventilation; TBV: Total blood volume; ICU: Intensive care unit.