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. 2023 Jun 12;14:1200017. doi: 10.3389/fphar.2023.1200017

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Copyright © 2023 Chen, Wu, Peng, Zhao, Dong, Ran, Geng, Zhang, Li, Huang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular subtyping based on CSC markers. (A, B) CDF curves and relative change under CDF curves when cluster number k was 2–10 in TCGA dataset. (C–E) Consensus matrix when k = 2 in TCGA (C), GSE39582 (D) and GSE17538 (E) datasets. (F–H) Kaplan-Meier survival curves of CSC1 and CSC2 for different survival time in TCGA (F) GSE39582 (G) and GSE17538 (H) datasets. (I) PCA plots of CSC1 and CSC2 in three datasets. OS, overall survival; DSS, disease-specific survival; DFI, disease-free interval; PFI, progression-free interval; RFS, recurrence-free survival; DFS, disease-free survival.