TABLE III. Genotype, mutant allele frequency, 95% confidence interval (CI), inbreeding coefficient (FIS), chi-square significance (p) for mutations V410L, F1534C, and V1016I in three populations of Aedes aegypti from Venezuela.
| Mutation | Population | N | Genotype | kdr Frequency (95% CI) | Hardy Weinberg Disequilibrium | |||
| Mutant allele | Heterozygote | Wild type | FIS | p-value | ||||
| V410L | LL | VL | VV | |||||
| Las Brisas a | 72 | 5 | 12 | 55 | 0.15 (0.10-0.22) | 0.36 | 0.0025 | |
| Urbanización 19 de Abril a | 154 | 3 | 40 | 111 | 0.15 (0.11-0.19) | -0.02 | 0.7826 | |
| Nacupay b | 96 | 0 | 1 | 95 | 0.01 (0.00-0.03) | -0.01 | 0.9591 | |
| F1534C | CC | FC | FF | |||||
| Las Brisas a | 72 | 70 | 0 | 2 | 0.97 (0.93-0.99) | 1 | < 0.0001 | |
| Urbanización 19 de Abril a | 155 | 155 | 0 | 0 | 1.00 (0.99-1.00) | NA | NA | |
| Nacupay b | 96 | 55 | 2 | 39 | 0.58 (0.51-0.65) | 0.96 | < 0.0001 | |
| V1016I | II | VI | VV | |||||
| Las Brisas a | 72 | 8 | 11 | 53 | 0.19 (0.13-0.26) | 0.50 | < 0.0001 | |
| Urbanización 19 de Abril a | 151 | 3 | 41 | 107 | 0.16 (0.12-0.20) | -0.03 | 0.684 | |
| Nacupay b | 96 | 1 | 2 | 93 | 0.02 (0.01-0.05) | 0.49 | < 0.0001 | |
a: Las Brisas and Urbanización 19 de Abril phenotype = permethrin resistant; b: Nacupay phenotype = permethrin susceptible.