Normalized mass of the major hindlimb muscles post-injury. A: soleus atrophy was blunted with boldine at 7 days but not 28 days post-SCI. SCI led to similar magnitudes of muscle loss with and without boldine for the plantaris (B), gastrocnemius (C), EDL (D), and TA (E). Individual data points are presented in violin plots with 95% confidence interval boundaries. The solid black line represents the median value and hashed lines represent quartiles. Tukey’s multiple comparison test was used for interaction follow-up with a denoting statistical differences vs. 7 days Sham, b vs. 28 days Sham and c vs. 7 days SCIb. EDL, extensor digitorum longus; SCI, spinal cord injury; TA, tibialis anterior.