Figure 3.

Diurnal rhythmicity of blood pressure is dampened during prolonged environmental circadian disruption (ECD) pressures were continuously measured by telemetry and averaged in 1-h bins through the end of the experiment (n = 3 rats/group). Cosinor (rhythm) daily amplitude, expressed as percentage of mesor for systolic (SBP; A) and diastolic (DBP; B) blood pressures are plotted for each day of the study (means ± SE of n = 3 rats/group). Post hoc statistical daily comparisons are indicated by *P < 0.05 and #P < 0.1 and suggest that the amplitude (day/night change) is suppressed intermittently after each shift of the light/dark cycle.