Table 3A.
Association of risk factors with eGFR change over time by Race Sex and Region
| Black | White | P interaction | |
|---|---|---|---|
| n | 4,198 | 7,799 | |
| Age* | −0.12 (<0.001) | −0.06 (<0.001) | 0.10 |
| Male sex | −0.02 (0.70) | 0.00 (0.97) | 0.77 |
| Black race | n/a | n/a | - |
| Education ≥ High School | 0.07 (0.41) | 0.13 (0.14) | 0.64 |
| Income ≥$35,000 | 0.10 (0.07) | 0.08 (0.07) | 0.68 |
| Stroke belt | −0.09 (0.08) | −0.12 (0.001) | 0.73 |
| Current smoking | −0.13 (0.09) | 0.01 (0.90) | 0.15 |
| Systolic blood pressure* | −0.11 (<0.001) | −0.10 (<0.001) | 0.82 |
| Body mass index* | −0.09 (<0.001) | −0.02 (0.25) | 0.04 |
| Diabetes | −0.61 (<0.001) | −0.39 (<0.001) | 0.01 |
| Hyperlipidemia | 0.15 (0.007) | 0.04 (0.28) | 0.10 |
| Cardiovascular Disease | 0.06 (0.54) | −0.11 (0.04) | 0.10 |
| Log Urine ACR* | −0.26 (<0.001) | −0.17 (<0.001) | 0.01 |
| Male | Female | ||
| n | 5,528 | 6,469 | |
| Age* | −0.11 (<0.001) | −0.05 (0.02) | 0.06 |
| Male sex | n/a | n/a | - |
| Black race | 0.02 (0.61) | 0.04 (0.39) | 0.83 |
| Education ≥ High School | 0.01 (0.93) | 0.18 (0.03) | 0.17 |
| Income ≥$35,000 | 0.14 (0.007) | 0.05 (0.28) | 0.21 |
| Stroke belt | −0.11 (0.009) | −0.10 (0.02) | 0.87 |
| Current smoking | −0.05 (0.50) | −0.05 (0.41) | 0.95 |
| Systolic blood pressure* | −0.09 (<0.001) | −0.11 (<0.001) | 0.56 |
| Body mass index* | −0.02 (0.37) | −0.06 (0.001) | 0.22 |
| Diabetes | −0.48 (<0.001) | −0.53 (<0.001) | 0.53 |
| Hyperlipidemia | 0.07 (0.13) | 0.10 (0.03) | 0.67 |
| Cardiovascular Disease | 0.00 (0.99) | −0.14 (0.07) | 0.13 |
| Log Urine ACR* | −0.19 (<0.001) | −0.23 (<0.001) | 0.25 |
| Stroke belt | Non-stroke belt | ||
| n | 6,682 | 5,315 | |
| Age* | −0.08 (<0.001) | −0.08 (<0.001) | 0.95 |
| Male sex | −0.02 (0.63) | 0.01 (0.88) | 0.67 |
| Black race | 0.05 (0.32) | 0.01 (0.84) | 0.59 |
| Education ≥ High School | 0.11 (0.17) | 0.13 (0.20) | 0.85 |
| Income ≥$35,000 | 0.09 (0.05) | 0.08 (0.12) | 0.90 |
| Stroke belt | n/a | n/a | - |
| Current smoking | 0.04 (0.53) | −0.17 (0.02) | 0.03 |
| Systolic blood pressure* | −0.09 (<0.001) | −0.12 (<0.001) | 0.48 |
| Body mass index* | −0.06 (0.004) | −0.03 (0.18) | 0.35 |
| Diabetes | −0.52 (<0.001) | −0.47 (<0.01) | 0.62 |
| Hyperlipidemia | 0.11 (0.01) | 0.06 (0.20) | 0.45 |
| Cardiovascular Disease | −0.02 (0.77) | −0.11 (0.12) | 0.34 |
| Log Urine ACR* | −0.25 (<0.001) | −0.16 (<0.0001) | 0.01 |
*
relative risk per one standard deviation increase: for age 8 years, for SBP 15 mmHg, for BMI 5.8 kg/m2, for albumin-to-creatinine ratio (ACR) 0.9 mg/g.