Table 2.
Hospital Course.
| Characteristic | Discharged home on ASM | |
|---|---|---|
| No (n=118) | Yes (n=184) | |
| Severity of HIEa | ||
| Moderate | 92 (78%) | 139 (76%) |
| Severe | 26 (22%) | 44 (24%) |
| Hypotension | 37 (31%) | 60 (33%) |
| Hypothermia treatment | ||
| Normothermia | 36 (31%) | 54 (29%) |
| Hypothermia 33.5°C × 72 hrs. | 25 (21%) | 51 (28%) |
| Hypothermia 32°C × 72 hrs. | 15 (13%) | 18 (10%) |
| Hypothermia 33.5°C × 120 hrs. | 14 (12%) | 17 (9%) |
| Hypothermia 32°C × 120 hrs. | 14 (12%) | 11 (6%) |
| Hypothermia ≥ 6 HOL | 14 (12%) | 33 (18%) |
| Persistent pulmonary hypertension | 33 (28%) | 34 (18%) |
| Oliguria or anuria | 28 (24%) | 43 (23%) |
| Hepatic dysfunction | 25 (21%) | 36 (20%) |
| Bloodstream infection / Septicemia | 2 (2%) | 4 (2%) |
| Use of EEG | 103 (87%) | 174 (95%) |
| Presence of EEG seizure among infants with EEGb | 28/82 (34%) | 74/127 (58%) |
| Days receiving oxygen (days)c | 5 (2–13) | 6 (2–13) |
| Length of stay (days)d | 17.5 (11–24) | 17 (12–25.5) |
| Abnormal neuro exam at discharge | 51 (46%) | 98 (57%) |
| Any abnormal additional findings at discharge | 43 (39%) | 71 (42%) |
| Discharge on tube/gavage feeds | 23 (19%) | 50 (27%) |
Data given as n (%) unless otherwise specified.
Abbreviations: ASM, anti-seizure medication; HIE, hypoxic-ischemic encephalopathy; HOL, hour of life; EEG, electroencephalogram; IH, induced hypothermia.
a
Severity of HIE is missing for 1 infant.
b
Presence of EEG seizure is missing for 68 infants, as data was not available for IH study.
c
Days of oxygen defined as need for any supplemental oxygen (>0.21) by any means for any portion of the day.
d
Length of stay defined as number of days between infants date of birth and date of discharge or transfer.