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. 2023 Jun 26;13:10371. doi: 10.1038/s41598-023-37412-6

Table 4.

Univariate analysis and different multivariate analysis models in which logarithmically transformed DAPSA score was used as a dependent variable.

B SE Beta t P
Model 1 (Univariate analysis)
 Log age 2.595 0.652 0.409 3.979 0.000
 Log BMI 2.395 1.360 0.196 1.762 0.082
 Log PSA duration 0.416 0.142 0.380 2.931 0.005
 Log uric acid 0.264 0.487 0.080 0.543 0.590
 Log CRP 0.549 0.105 0.604 5.253 0.000
 Log triglycerides 0.596 0.228 0.359 2.613 0.012
 Log BLC 0.103 0.311 0.044 0.331 0.742
 Log MIG 0.334 0.180 0.239 1.856 0.069
 Log IL17 0.561 0.102 0.551 5.486 0.000
 Log adiponectin 0.064 0.369 0.021 0.173 0.864
 Log Leptin 0.283 0.269 0.126 1.052 0.296
 Log rezistin −1.060 0.590 −0.211 −1.797 0.077
 Log GLS −5.920 1.011 −0.550 −5.854 0.000
 Log LVIDd 4.033 1.988 0.225 2.029 0.046
 Log LADiam 3.251 1.227 0.291 2.649 0.010
 Log TAPSE −5.436 0.824 −0.614 −6.600 0.000
 Log MV −1.175 0.436 −0.299 −2.695 0.009
 Log EE −0.189 0.811 −0.027 −0.233 0.816
Model 2 (Independent variables: Log age, Log CRP, Log triglycerides, Log IL-17, Log GLS)
 Log CRP 0.362 .109 0.478 3.308 0.002
 Log triglycerides 0.486 .218 0.318 2.226 0.033
Model 3 (Independent variables: Log GLS, Log IL-17, Log BLC)
 Log IL-17 0.398 0.112 0.397 3.542 0.001
 Log GLS −4.365 1.305 −0.375 −3.346 0.001
Model 4 (Independent variables: Log GLS, Log IL-17, Log BLC, Log BMI and Log age)
 Log IL-17 0.415 0.105 0.418 3.963  < 0.001
 Log GLS −3.210 1.264 −0.277 −2.539 0.014
 Age 0.045 0.015 0.303 3.065 0.003

B unstandardized coefficient; SE standard error; Beta Standard coefficient, DAPSA Disease Activity in Psoriatic arthritis, PSA psoriatic arthritis, GLS global longitudinal strain, IL-17 interleukin 17, CRP C reactive protein, BMI body mass indeks, LVIDd left ventricular internal diameter at end-diastole, LADiam left atrium diameter, TAPSE tricuspid annular plane systolic excursion, MV mitral valve, E/E early diastolic mitral inflow velocity to early diastolic mitral annulus velocity, GLS global longitudinal strain, BLC B lymphocyte chemoattractant, MIG monokine induced by intereferon gamma.

Model 1—Univariate analysis (LogDAPSA set as dependent variable, independent variables were comprised of all cytokines, echo parameters and other parameters with statistical significant difference in prior analyses).

Model 2—Regional multivariate analysis where LogDAPSA was used as dependent variable, while independent variables were comprised of all parameters that showed statistical significant association in univariate analysis (Log Age, Log CRP, Log triglycerides, Log IL-17, Log GLS).

Model 3—Regional multivariate analysis where LogDAPSA was used as dependent variable, while independent variables were chosen at author’s discretion based on previous analyses (Log GLS, Log IL-17, Log BLC).

Model 4—Regional multivariate analysis where LogDAPSA was used as dependent variable, while independent variables were chosen at author’s discretion based on previous analyses (Log GLS, Log IL-17, Log BLC, BMI and age).