Table 2.
The results of metabolic pathway analysis
| Pathway name | Totala | Hitsb | Raw pc | -Log(p) | Impactd | Detected metabolites |
|---|---|---|---|---|---|---|
| Phenylalanine metabolism | 12 | 3 | 0.0013 | 2.899 | 0.619 | l-Phenylalanine; phenylpyruvate; ortho-hydroxyphenylacetic acid |
| Phenylalanine, tyrosine, and tryptophan biosynthesis | 4 | 2 | 0.0023 | 2.646 | 0.500 | Phenylpyruvate; l-phenylalanine |
| Arachidonic acid metabolism | 36 | 1 | 0.0282 | 1.550 | 0.333 | Arachidonate |
| Sphingolipid metabolism | 21 | 1 | 0.0005 | 3.266 | 0.045 | Sphingosine |
| Glycerophospholipid metabolism | 36 | 1 | 0.0147 | 1.834 | 0.017 | LysoPC(17:0) |
| Steroid hormone biosynthesis | 77 | 1 | 0.0266 | 1.575 | 0.007 | Cortisone |
| Biosynthesis of unsaturated fatty acids | 36 | 3 | 0.0054 | 2.268 | 0.000 | Arachidonate; DHA; EPA |
| Aminoacyl-tRNA biosynthesis | 48 | 1 | 0.0196 | 1.707 | 0.000 | l-Phenylalanine |
| Metabolism of xenobiotics by cytochrome P450 | 64 | 1 | 0.0287 | 1.543 | 0.000 | 1-Nitro-5,6-dihydroxy-dihydronaphthalene |
aTotal is the total number of compounds in the metabolic pathway
bHits is the number of actual matches in the user uploaded data
cRaw p is the raw P value calculated from the enrichment analysis
dImpact is the pathway impact value calculated by the pathway topology analysis