Table 3.

Factors predicting pituitary function improvement and worsening

	Factors predicting recovery of at least 1 hormonal axis (N = 42/122)				Factors predicting appearance of at least 1 new hormonal deficiency (N = 13/122)
	Univariate analysis		Multivariate analysis		Univariate analysis
	OR (95% CI)	p value	OR (95% CI)	p value	OR (95% CI)	p value
Gender (female)	0.51 (0.23–1.15)	0.104	0.27 (0.10–0.71)	0.009	0.997 (0.31–3.25)	0.996
Age (per 5 years)	1.12 (0.98–1.30)	0.106	1.14 (0.98–1.34)	0.095	1.16 (0.92–1.45)	0.214
Tumor size prior to surgery—maximal diameter (per 5 mm)	0.95 (0.75–1.19)	0.637			1.06 (0.75–1.49)	0.749
Average diameter decrease with surgery (at least 50% decrease)	1.07 (0.45–2.56)	0.882			0.79 (0.22–2.77)	0.712
Hyperprolactinemia	2.09 (0.96–4.57)	0.064	3.45 (1.38–8.64)	0.008	1.57 (0.48–5.12)	0.455