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HD-MTX-related hematological toxicities by cycle number.
| Toxicity | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 3/4 |
|---|---|---|---|---|---|---|
| Leukopenia | 13 (1.99%) | 47 (7.19%) | 108 (16.51%) | 172 (26.30%) | 314 (48.01%) | 486 (74.31%) |
| Anemia | 23 (3.52%) | 226 (34.56%) | 232 (35.47%) | 162 (24.77%) | 11 (1.68%) | 173 (26.45%) |
| Thrombocytopenia | 460 (70.34%) | 37 (5.66%) | 29 (4.43%) | 41 (6.27%) | 87 (13.30%) | 128 (19.57%) |
HD-MTX, high-dose methotrexate.
