Table 1.
NTMTs crystal structures that are deposited in the PDB
| Methyltransferase | PDB | Cocrystallized molecules |
|---|---|---|
| NTMT1 | 2EX4 | SAH |
| 6KDQ | CENP-A monomethylated peptide | |
| 5CVD | CENP-A dimethylated peptide | |
| 5CVE | SAH, fly histone 2B peptide | |
| 7K3D | DC113 | |
| 6DTN | NAH-C3-PPKRIA | |
| 6WH8 | BM30 | |
| 6WJ7 | NAH-C2-GPARIA | |
| 6PVA | NAH-C3-GPKK | |
| 6PVB | NAH-C5-GPKRIA | |
| 5E2A, 5E1M, 5E1O, 5E1B, 5E1D, 5E2B | SAH, RCC1 peptide | |
| NTMT2 | 5UBB | SAM |
| 6DUB | SAH, RCC1 peptide | |
| Ntm1 | 7D8F | SAH |
| 7D8D | SAH, Rps25a peptide |
Abbreviations: NAH, N-adenosyl-L-homocysteine; NTMT, N-terminal methyltransferase; SAH, S-adenosyl-L-homocysteine; SAM, S-adenosyl-L-methionine.