TABLE 1.

The eight clinical facial signs of Caucasian women, related to wrinkles/texture, ptosis/sagging, or vascular signs.

Facial Signs	Definition of scored observation	Scale	Visual
Glabellar wrinkles	Depth of vertical wrinkles between eyebrows.	0–5
Crow's feet wrinkles	Depth of deepest wrinkle at the area of outer eye corner (5 mm at least outside from the corner).	0−6
Periorbital wrinkles (upper cheek area)	Depth of folds at the malar area below Crow's feet, eye orbit excepted.	0−5
Nasolabial fold	Depth of the fold present on the face between the base of the nose and lips.	0−5
Cheek folds	Depth of folds in the cheek area.	0−8
Marionette lines	Depth of folds at the corner of lips.	0−6
Ptosis of the lower part of the face	Sagging severity of the lower parts of each side of the chin.	0−5
Vascular signs	Diffused redness and microvessels are visible on the face and especially the cheeks.	0−7