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. 2023 Jun 15;14(6):846–861. doi: 10.4239/wjd.v14.i6.846

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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Metabolomic analysis of Lomatogonium rotatum-treated streptozotocin-induced diabetic rats. A: The Venn diagram displays the amount of metabolites with differential expression. Different colors indicate distinct comparisons, whereas overlapping regions show differentially expressed metabolites shared by two groups; B: Serum metabolic characteristics of different groups were determined by a principal component analysis diagram; C: Cluster heat map of differentially-expressed metabolites in three experimental groups. In each sample, red and blue colors indicated higher and lower expression, respectively. LR: Lomatogonium rotatum; QC: Quality control.